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Evolution evolutionary selection

The desire to create RNA molecules with predefined properties and to optimize their efficiencies and specificities has led to a new technique called evolutionary biotechnology or applied molecular evolution. Natural selection or its analogue in test-tube evolution optimizes fitness or replication rate constants, respectively. High replication rates, however, are neither required nor wanted in the search for... [Pg.176]

The present hypothesis assumes interaction between receptors and secondary metabolites. As a consequence receptor evolution reflects an evolutionary selection in secondary metabolites. The main lines in the chemical evolution of living systems, the RN A-world developing to a breakthrough organism, the ancestor of the progenote from which the three kingdoms, archaebacteria, eubacteria, and eucaryotes evolved (195) are established. Within each kingdom the biochemical evolution is still almost... [Pg.722]

Keywords. Adaptation, Directed evolution. Evolutionary engineering. Metabolic engineering. Selection... [Pg.129]

Religion arose thousands of years after the fundamentals of morality evolved in animals. F. B. states, The profound irony is that our noblest achievement - morality - has evolutionary ties to our most base behavior - warfare. Immanuel Kant believed that morality is based on reason, whereas David Hume argued that moral judgments proceed from emotions. DeWaal believes that, Human behavior derives above all from fast, automated, emotional judgments, and only secondarily from slower conscious processes. Emotions are our compass, shaped by evolution. Natural selection favors organisms that survive and reproduce. [Pg.195]

Aptamers are oligonucleotides (DNA or RNA molecules) which are able to bind selectively to low-molecular-weight molecules or to macromolecules such as proteins. The interest in aptamers as ligands is related to their ease of preparation by an evolutionary selection procedure that eliminates the need for structural design of the ligand sites. Selection of the aptamers for the specific target is based on the SELEX (systematic evolution of ligands by exponential enrichment) procedure. [Pg.29]

Finally, when we speak about evolutionary selection of a particular molecule for a given function, we do not mean to imply that evolution operates on a molecular level. Evolution, of course, takes place at the level of organism populations, and molecules are selected only in the sense that their use gives the organism an increased likelihood of surviving and procreating. [Pg.1013]

Several groups have taken proteins at the beginning and end of an evolutionary path,... M. Lunzer et al. The biochemical architecture of an ancient adaptive landscape. 2005. Science 310(5747), pp. 499-501 and S. Noor et al. Intramolecular epistasis and the evolution of a new enzymatic function. 2012. PLoS One 7(6), p. e39822. DOI 10.1371/jour-nal.pone.0039822 for the order in which proteins assemble J. A. Marsh et al. Protein complexes are under evolutionary selection to assemble via ordered pathways. 2013. Cell 153(2), p. 461. DOI 10.1016/j.cell.2013.02.044 see also F. J. Poelwijk et al. Empirical fitness landscapes reveal accessible evolutionary paths. 2007. Nature 445(7126), p. 383. [Pg.315]

Our dependence on evolutionary methods of strain improvement, such as those described in Section 18.2.4, demonstrates Orgel s second rule that evolution is cleverer than you are. When we lack the information needed for rational design, we can build improved strains by evolution and selection of expression libraries. But in order to learn from these improved strains, we must invest the effort in identifying and understanding the key mutations, so that these new design strategies can be implemented into other strains. [Pg.561]

Although natural selection is the only evolutionary agent that adapts organisms to their environments, the course of evolution has been profoundly influenced by major environmental changes, some of which had catastrophic effects. Some of these events resulted from Earth s internal processes, such as the activity of volcanoes and the shifting and colliding of continents. Others were the result of external events, such as collision of meteorites with Earth. [Pg.41]

When evolution selects the genes that build the parts of brains (modules) that produce a particular kind of behaviour, and evolution selects them because of the fitness benefits of that kind of behaviour, we have the conditions for a perfect evolutionary psychological explanation. [Pg.236]


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Evolution selection

Selection, evolutionary

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