Eupentacta fraudatrix

Cucumarioside Gi (8) and cucumarioside G2 (15) are native glycosides from the sea cucumber Eupentacta fraudatrix. Substances 3, 4, 5, 6, 7, 9 and 10 are derivatives of cucumariosides Gi- Substances 11 and 12 are dihydroderivatives of cucumariosides C2 and H from E. fraudatrix, correspondingly. Frondoside A (2) is a glycoside from the Cucumaria frondosa, cucumarioside A4-2 (13) is a glycoside from Cucumaria japonica, and the substance 14 is a derivative of cucumarioside A4-2. The data are shown in Table 1. 

These results showed that sulfate groups, attached to different positions of the carbohydrate chain differently influence on the hemolytic activity and loss. A sulfate group, attached to C-4 of the first xylose of branched pentaosides having 3-O-methyl group in terminal monosaccharide unit, increases the activity by kinetic parameters of hemolysis and by loss rate. Similar results were obtained by us for glycosides from Eupentacta fraudatrix [33]. 

Two new diterpenic glycosides, virescenosides M 9 and N 10, were isolated from the marine fungus Acremonium striatisporum KMM 4401 which was associated with the holothurian Eupentacta fraudatrix. They both exhibited cytotoxic action against tumor cells of Ehrlich carcinoma in vitro, and showed a cytotoxic effect on developing eggs of the sea urchin Strongylocentrotus intermedius. 

Eupentacta fraudatrix [63] and Eximisoside A from Psolus eximius [64]. In frondoside A2-2 (49a), the simultaneous presence of a 24-ketone conjugated with a double bond in the side chain is a unique characteristic for holothurins. 

Pentasaccharide with 3-O-methyl-D-xylose Cueumariosides (triterpene) Sea cucumber Eupentacta fraudatrix 326... 

Recent studies show that in many holothurian species, as in Eupentacta fraudatrix, the sterol composition is complex, the number of identified structures ranging from 70 to 80 (Stonik et al., 1998 Ponomarenko et al., 2001). Some free sterol compositions are presented in Table 26.15, and the structural elements are shown in Figure 26.23. The compositions given here are limited to sterols that account for at least 1% of the total sterol fraction other publications give only the qualitative composition, such as Goad et al, 1985,1986 for Psolusfabricii. 

Cladolabes bifurcatus Cucumaria sp. Eupentacta fraudatrix Bathyplotes natans Holothuria nobilis Holothuria scabra Pseudostichopus trachus Synapta maculata" Trochostoma orier)tale ... 

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