Eunicellin diterpenoids

Marine organisms have again continued to provide some-very unusual diterpenoids. The sea-pen, Stylatula sp., was the source of the compounds (72) and (73). X-Ray analysis has shown that cleomeolide, from Cleome icosandra, has the structure (74). A further diterpenoid related to eunicellin, ophirin (75), has been obtained from a Muricella sp. A full paper on the ether dictyoxide (76) has appeared. ... 

Kashman, Y. A New Diterpenoid Related to Eunicellin and Cladiellin from a Muricella sp. Tetrahedron Lett. 21, 879 (1980). 

Hassan, H.M., Khanfar, M.A., Elnagar, A.Y., Mohammed, R., Shaala, L. A., Youssef, D.T.A., Hifnawy, M.S., and El Sayed, K.A. (2010) Pachycladins A-E, prostate cancer invasion and migration inhibitory eunicellin-based diterpenoids from the Red Sea soft coral Cladidla pachydados. ]. Nat. Prod., 73,848-853. 

Kakonikos, C., Vagias, C., Roussis, V, Roussakis, C., and Komprobst, J.M. (1999) New eunicellin-type diterpenoids from the gorgonian coral Eunicella labiata. Nat. Prod. Lett., 13, 89-95. 

Kennard, O., Watson, D.G., Di Sanseverino, L.R., Tiusch, B Bosmans, R., and Djerassi, C. (1968) Chemical studies of marine invertebrates. IV. Terpenoids LXII. Eunicellin, a diterpenoid of the gorgonian Eunicella stricta X-ray diffraction analysis of eimicellin dibromide. Tetrahedron Lett, 9, 2879-2884. 

Uchio, Y, Kodama, M., Usui, S., and Fukazawa, Y. (1992) Three new eunicellin-based diterpenoids from an Okinawan CladieUa spedes of soft coral. Tetrahedron Lett., 33,1317-1320. 

Yamada, K., Ogata, N Ryu, K, Miyamoto, T., Komori, T., and Higuchi, R. (1997b) Bioactive terpenoids from Octocorallia. 3. A new eunicellin-based diterpenoid from the soft coral Cladiella sphaeroides. 

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