Phenobarbital Etoposide

Aflatoxin Bl, bupropion, cyclophosphamide, dexamethasone, etoposide, ifosfamide, midazolam, phenobarbital, propofol, rifampin, teitiposide, thiotepa, vitamin D, xenobiotics Amitriptyhne, carisoprodol,... [Pg.276]

Sodium phenobarbital Oxathiin carboxanilide Physostigmine Perilla ketone (NSC 348407) Peptides Somatotropin Physostigmine Etoposide Bleomycin... [Pg.208]

ETOPOSIDE ANTIEPILEPTICS - PHENYTOIN, PHENOBARBITAL Significantly i plasma concentrations of etoposide (clearance may be >170%) and considerable risk of loss of therapeutic efficacy Due to potent induction of the hepatic microsomal enzymes that metabolize etoposide Do not co-administer. Consider use of alternative antiepileptics that do not induce hepatic microsomal enzymes, e.g. valproic acid... [Pg.303]

Etoposide and teniposide are substrates of CYP3A4, and their clearance rate is increased by inducers such as car-bamazepine, phenobarbital, phenytoin, rifampicin, and St. John s wort (49,51-54,156). [Pg.3462]

Clinically important, potentially hazardous interactions with aluminum, aminophylline, carbamazepine, carbimazole, cyclosporine, daclizumab, diuretics, etoposide, etretinate, grapefruit juice, indomethacin, isoniazid, itraconazole, ketoconazole, licorice, live vaccines, methotrexate, naproxen, oral contraceptives, pancuronium, phenobarbital, phenytoin, rifampicin, troleandomycin... [Pg.473]

Etoposide clearance appears to be increased by phenobarbital, phenytoin, and probably carbamazepine, and this may result in reduced efficacy. [Pg.629]

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