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Etonogestrel

Molecular formula C22H28O2 Molecular weight 324.46 CAS Registry No 54048-10-1 Merck Index 13,3916 [Pg.238]

Sample preparation Extract medium twice with 2 mL diethyl ether. Evaporate the extracts to dryness, reconstitute the residue with MeOH, inject an aliquot. [Pg.238]

Mobile phase MeCN MeOH 0.5% pH 3.0 ammonium dihydrogen phosphate 15 47 38 Flow rate 1.2 Detector UV 214 [Pg.238]

Rudland, P.S. Back, D.J. Metabolism of the oral contraceptive steroids ethynylestradiol, norgestimate and 3-ketodesogestrel by a human endometrial cancer ceU line (HEC-IA) and endometrial tissue in vitro, J.Steroid Biochem.Mol.Biol., 1993, 45, 407-420. [Pg.238]

Guard column Novapak C18 Column 150 x 3.9 Novapak C18 Column temperature 50 [Pg.238]

The NuvaRing is a unique transvaginal delivery system that provides 15 meg ethinyl estradiol and 120 meg etonogestrel for the prevention of ovulation. The NuvaRing is inserted into the vagina on or before day 5 of the menstrual cycle and is removed... [Pg.746]

In vitro data show that both etonogestrel and ethinyl estradiol are metabolized in liver microsomes by the cytochrome P450 3A4 isoenzyme. Etonogestrel and ethinyl estradiol are primarily eliminated in urine, bile, and feces. [Pg.214]

Ethinyl Estradiol Norelgestromin (Ortho Evra) Etonogestrel subdermal Implant (Implanon)... [Pg.52]

Etonogestrel/Ethinyl Estradiol (NuvaRing) Medroxyprogesterone (Provera, Depo-Provera) Norgestrel (Ovrette) Oral Contraceptives, (Table VI-4)... [Pg.52]

Only one implantable contraceptive preparation is available at present in the USA. Etonogestrel, also used in some oral contraceptives, is available in the subcutaneous implant form listed in Table 40-3. Several hormonal contraceptives are available as vaginal rings or intrauterine devices. Intramuscular injection of large doses of medroxyprogesterone also provides contraception of long duration. [Pg.907]

The progestin implant method utilizes the subcutaneous implantation of capsules containing etonogestrel. These capsules release one fifth... [Pg.911]

Implanon, which became available in 1999, is a subdermal implant that contains 68 mg of etonogestrel, the active metabolite of desogestrel. The product and field experience is therefore still limited. During the first 2 years after implantation, there is no ovulation ovulation occurs occasionally in the third year, and it is recommended that the... [Pg.254]

Timmer, C.J., and T.M.T. Mulders. 2000. Pharmacokinetics of etonogestrel and ethinylestradiol released from a combined contraceptive vaginal ring. Clin Pharmacokin 39 233. [Pg.437]

Ethinyl estradiol Etonogestrel NuvaRing (vaginal ring)... [Pg.451]

See other pages where Etonogestrel is mentioned: [Pg.389]    [Pg.389]    [Pg.391]    [Pg.553]    [Pg.339]    [Pg.351]    [Pg.352]    [Pg.198]    [Pg.199]    [Pg.210]    [Pg.212]    [Pg.214]    [Pg.160]    [Pg.160]    [Pg.470]    [Pg.257]    [Pg.906]    [Pg.160]    [Pg.160]    [Pg.253]    [Pg.254]    [Pg.256]    [Pg.257]    [Pg.258]    [Pg.413]    [Pg.414]    [Pg.427]    [Pg.449]    [Pg.131]    [Pg.133]   
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Etonogestrel subdermal implant

Etonogestrel subdermal implant Implanon)

Etonogestrel/ethinyl estradiol

Etonogestrel/ethinyl estradiol NuvaRing)

Implanon (etonogestrel subdermal

NuvaRing (etonogestrel/ethinyl

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