Ethylene biosynthesis from

Watanabe T, Kondo N (1976) Isolation of a proteinaceous inhibitor of ethylene biosynthesis from marine algae. Agric Biol Chem 40 1877-1878 Webster PL (1967) Cell cycle kinetics in meristems Effects of colchicine and lAA. PhD Thesis, Case-Western Res Univ, Cleveland, Ohio Webster PL, Langenauer HD (1973) Experimental control of the activity of the quiescent centre in excised root tips of Zea mays. Planta 112 91-100 White KL, Hill AC, Bennett JH (1974) Synergistic inhibition of apparent photosynthesis rate of alfalfa by combinations of sulfur dioxide and nitrogen dioxide. Environ Sci Technol 8 574-576... 

Ethylene Biosynthesis from 1-Amino-i clopropanecarboxylic Acid Interplay of Molecular Genetics and Organic Mechanism... 

PIRRUNG Ethylene Biosynthesis from I Amuuxydopropanecarboj ic Acid 437... 

PIRRUNG Ethylene Biosynthesis from l-Aminocychpropanecarbox ic Acid 447... 

The nonprotein amino acid, 1-aminocyclopropane-l-carboxylic acid, is an intermediate of ethylene biosynthesis in plants. This amino acid is synthesized from the L-a-amino acid methionine through the intermediate 5 -adenosyl-L-methionine (SAM) (Scheme 8). ... 

The possibility that many organic compounds could potentially be precursors of ethylene was raised, but direct evidence that in apple fruit tissue ethylene derives only from carbons of methionine was provided by Lieberman and was confirmed for other plant species. The pathway of ethylene biosynthesis has been well characterized during the last three decades. The major breakthrough came from the work of Yang and Hoffman, who established 5-adenosyl-L-methionine (SAM) as the precursor of ethylene in higher plants. The key enzyme in ethylene biosynthesis 1-aminocyclopropane-l-carboxylate synthase (S-adenosyl-L-methionine methylthioadenosine lyase, EC 4.4.1.14 ACS) catalyzes the conversion of SAM to 1-aminocyclopropane-l-carboxylic acid (ACC) and then ACC is converted to ethylene by 1-aminocyclopropane-l-carboxylate oxidase (ACO) (Scheme 1). 

The ACS function is known only in higher plants. The activity of ACS isozymes is a key regulatory factor of ethylene biosynthesis pathway. In general, microorganisms liberate ethylene but their ethylene synthesis pathways do not involve ACC as an intermediate. Penicillium citrinum is the first reported microorganism that is able to synthesize ACC from SAM and to degrade it into ammonia and a-ketobutyrate, not to ethylene. ACS from P. citrinum shows a 100-fold higher for SAM than its plant counterparts. ... 

Grossmann K, Kwiatkowski J, Evidence for a causative role of cyanide, derived from ethylene biosynthesis, in the herbicidal mode of action of quinclorac in barnyard grass, Pestic Biochem Physiol 51 150-160, 1995. 

The most commercially successful PGRs are those that operate either through the inhibition of gibberellin biosynthesis, from mevalonic acid (Knee, 1982) or through the production of ethylene. These represent the two most valuable pathways for growth modification since they have key roles in extension growth, ripening, fruit set and dominance. 

The pathway of ethylene biosynthesis in higher plants is from l-methionine4 (Figure 5.9). Methionine is an intermediate in other metabolic processes and the control of ethylene biosynthesis via the interference of methionine production is not realistic. The ACC synthase step from S-adenosyl methionine to ACC appears more susceptible to chemical modification auxin promotes ethylene production by increasing the activity of ACC synthase. Subsequent steps from ACC are less controlled and ethylene is readily produced from the conversion of ACC in most tissues. 

Yu and Wang431 considered that indole-3-acetic acid exerts its stimulating effect on expansion growth by inducing the synthesis of the enzyme catalyzing the conversion of S-adenosylmethionine into ACC, a conclusion at variance with the suggestion of Vioque and coworkers432 that indoleacetic acid oxidase and its substrate (IAA) participate in the last reaction in the ethylene biosynthesis pathway, namely, the formation of ethylene from ACC. 

Aminocyclopropane carboxylic acid (6) has been detected in several plant tissues a procedure for preparing 6 from agricultural wastes, by extraction with a diluted solution of sulfosalicylic acid, has been described . 6 was established to be an intermediate product in ethylene biosynthesis " . Ethylene acts as a phytohormone which is involved in many metabolic processes in plants, e.g. in ripening, in stress situations or after wounding (see review and references cited therein). Natural 6 is formed from methionine via sulfonium salt (640) only S,S-(640) acted as a substrate for aminocyclopropanecarbo-xylate synthase, the S,R and R,R isomers of 640 were inactive as substrates . 6 can be... 

The production of berberine in cell suspension cultures of T. minus was regulated by ethylene via the activation of berberine biosynthesis from (S)-reticuline. However, ethylene promoted the formation of bound polyphenolics that are associated with cell browning when added in the late stage of culture [157]. 

Hottiger, T., Boiler, T 1991. Ethylene biosynthesis in Fusarium oxysporum f. sp. tulipae proceeds from gluta-mate/2-oxoglutarate and requires oxygen and ferrous ions in vivo. Arch. Microbiol. 157, 18-22,... 

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