Ethyldiisopropyl amine

The condensations were catalyzed by bases, such as alkali hydroxide or alkoxide, triethylamine, and piperidine or its acetate. Some reactions (75AG840 88AP757) proceed much more smoothly with diethyl acetone-dicarboxylate (even in the presence of diethylamine or ethyldiisopropyl-amine) than with, e.g., dibenzylketone (only in the presence of potassium hydroxide/morpholine or DBU). Yields vary significantly because side reactions are possible. 

Spherisorb CN Hexane/dichloromethane/ methanol //V-ethyldiisopropyl-amine (60 40 01 0.1) Tunaxanthins 56... 

Titanium enolates. These enolates have generally been prepared by transmet-talation of alkali-metal enolates or silyl enolate ethers. Surprisingly, Evans et al. find that a titanium enolate can be prepared directly from the oxazolidinone 1 by reaction with TiCl4 (1 equiv.) in CH2C12 and shortly thereafter with ethyldiisopropyl-amine (or triethylamine) at 0°. The enolate may actually be an ate complex (2a)... 

Phthalic anhydride Ethyldiisopropyl amine Acetic acid Thiourea n-Propanal Hydrobromic acid... 

HETEROCYCLES Copper phcnylace-tylide. Dichlorobis(benzonitrile)palladium. N-Dichloromethylene-N,N-dimcthylammo-nium chloride. Diiminosuccinonitrile. Dimethyl acetylenedicarboxylate. Dipotassium cyanodithioimidocarbonate. Ethoxy-carbonyl isothiocyanate. Ethyldiisopropyl-amine. Ethylene oxide. Hydrogen fluoride. Isocyanomethane-phosphoric acid diethyl ester. Lead tetraacetate. Lithium aluminium hydride. Methylhydrazine. Phosphoryl chloride. Polyphosphate ester. Polyphosphoric acid. Potassium amide. Potassium hydroxide. Tolythiomethyl isocyanide. Tosylmethyl isocyanide, Trichlo-romethylisocyanide dichloride. Trimethyl-silyldiazomethane. 

TBDMSCl, DMAP, EtjN, DMF, 25°C, 12 h. These conditions were used to silylate selectively a primary over a secondary alcohol. In the silylation of carbohydrates, it was shown that these conditions inhibit silyl migration whereas the use of imidazole as base causes migration." Besides DMAP, other catalysts such as 1,1,3,3-tetramethylguanidine, l,8-diazahicyclo[5.4.0]undec-7-ene (83-99%), l,5-diazabicyclo[4.3.0]non-5-ene, and ethyldiisopropyl-amine have also been used. A chiral guanidine has been used to give modest kinetic resolution of chiral secondary alcohols with TBDMSCl and TIPSCl. ... 

Treatment of the 1,3-dithiolane S-oxide (149) with iodotrimethylsilane and ethyldiisopropyl amine results in an efficient dehydration and yields the corresponding dithioles (150) (Equation... 

The analytically pure 1,2,3-thiadiazinium salt 4a was suspended in MeOH (15 mL) and ethyldiisopropyl-amine (1 g) was added with stirring. Stirring was continued at rt for 1 h and then 5 a was isolated by suction filtration. The salt 4b was suspended in MeOH (20 mL) and a solution of KOH (5 mmol) in MeOH (10 mL) was added. After brief stirring, the analytically pure 1,2,3-thiadiazinc 5b was isolated by suction filtration. 

Steroids possessing one or two isolated or conjugated double bonds are converted into their dihydrogen phosphates when brought into contact with (l-phenyl-l,2-dibromoethyl)phosphonic acid in the presence of ethyldiisopropyl-amine. The reactions presumably involve monomeric metaphosphate ion as the effective phosphorylating agent. ... 

Peptides. A mixture of N-benzyloxycarbonyl-L-phenylalanine, ethyl glycinate hydrochloride, triphenylphosphine, bromotridiloromethane, and ethyldiisopropyl-amine refluxed 3 hrs. in tetrahydrofuran ethyl N-benzyloxycarbonyl-L-phenyl-alanylglycinate. Y 85%. F. e. and procedure, also with CCI4 instead of CBrClg, s. L. E. Barstow and V. J. Hruby, J. Org. Chem. 36, 1305 (1971). 

PA 6.6 membranes were stirred with a solution of 1.8 mmol N-ethyldiisopropyl amine and 1.8 mmol dicarbonic acid dichloride in 3 ml ether for 30 min. Residual acid chloride groups were hydrolysed with 0.5 M NaHC03 solution. The membranes were rinsed with deionised water. 

---