Ethylamine dehydrogenation

Ethylamine is not as readily metabolized as methyla-mine, and portions are excreted unchanged from the lung and in the urine. The metabolism of ethylamine is believed to occur in two stages. The amino group is initially dehydrogenated to an intermediate imine (ethyl imine), which reacts spontaneously with water, forming the corresponding aldehyde (acetaldehyde) and ammonia. The final metabolic products of acetic acid and urea are excreted in the urine. Ethylamine is a normal constituent of mammalian and human urine. 

Lithium-ethylamine reduction at one or both double bonds of carvone, and of carvenone (58) to carvomenthone only, is reported.The effect of solvent on the lithium or potassium amide-reduction of p-cymene to menthenes and menthadienes has been examined.Hydrogenation of carvone (Vol. 4, p. 32), using palladium-polysaccharide exchange resin, favours endocyclic over exocyclic double-bond reduction, more so than with Pd-C or Pd-BaS04, whereas platinum or rhodium on exchange resins exhibit no special selectivity.Optimum conditions for the catalytic hydrogenation of thymol, and the catalytic dehydrogenation of menthol, to menthone have been determined.Cathodic reduction of carvomenthone (to... 

From this study the following reaction scheme describing the transformation of ethylamine to the main product DMEA and by-products was established. From a kinetic point of view, steps 2 and 3 are the rate determining reactions. It follows that the DMEA selectivity is increased by modifying the acido-basicity of copper chromite used as a catalyst. In fact, the change of the catalyst basicity can decrease the MEA condensation to form DEA without modification of the hydro-dehydrogenating properties of the catalyst which are necessary for the methylation of ethylamine with methanol (steps 1 and 3). 

The third sesquiterpene isonitrile in Chart 5 has been isolated from the extracts of Acanthella acuta, which also yielded a number of minor compounds 138). The major component, acanthellin-1, proved to have a 4-epi-eudesmane structure (49). The carbon skeleton was deduced by lithium/ethylamine reduction, which afforded a saturated bycyclic hydrocarbon (60) converted into eudalene by drastic dehydrogenation. The i.r. 

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