Ethyl p-toluidine

Methylaniline Ethylaniline n-Propylaniline n-Butylaniline Benzylaniline 2 -MethyIbenzylamine N-Ethylbenzylamine 2 -Methyl o-toluidine N-Methyl m-toluidine 2 -MethyI p-toluidine N-Ethyl o-toIuidine N-Ethyl m-toIuidine 2S -Ethyl p-toluidine 2 -MethyI a-naphthylamine N-Methyl p-naphthylamine N-Phenyl- a-naphthylamine 2 -Phenyl-P-naphthylamine... 

Ethy Ibenzy lamine A -Methyl o-toluidine A -Methyl m-toluidine. 2V-Methyl p-toluidine A -Ethyl o-toluidine -Ethyl m-toluidine -Ethyl p-toluidine 2V-Methyl a-naphthylamine 2V-Methyl p-naphthylamine 2V-Phenyl- a-naphthylamine N-Phenyl- p-naphthylamine... 

V-Ethylbenzylamine A -Methyl o-toluidine TV-Methyl m-toluidine. A7-Methyl p-toluidine A7-Ethyl o-toluidine A7-Ethyl m-toluidine A7-Ethyl p-toluidine A7-Methyl a-naphthylamine. . ZV-Methyl p-naphthylamine. 2V-Phenyl-a-naphthylamine. N-Phenyl- p-naphthylamine. ... 

Recently Fujiwara and co-workers [16] found that the nitration of A/,VV-diu ethyl-p-toluidine in 70-77% sulphuric acid proceeds by a formation of the o complex through the /pso-attack (on ipso-nitration see p. SO) and after that dte km is rearranged to the nitro compound (2) ... 

Secondary arylamines give products of attack at nitrogen as well as ring-substitution products. Thus, A -methylaniline reacts with formaldehyde and piperidine in the absence of acids to afford the aminal (6). In the presence of 0.5 mol equiv. of acetic acid the ring-substitution product (7) is obtained in 40% yield. Another type of aminal has also been obtained in reactions of secondary arylamines (V-ethyl-p-toluidine gives the important by-product (8) in a reaction with piperidine and formaldehyde. ... 

Methylaniline Ethylaniline n-Propylaniline n-Butylaniline Benzylaniline AT-Methylbenzylamine N -Ethy Ibenzy lamine AT-Methyl o-toluidine M-Methyl m-toluidine iV-Methyl p-toluidine Al-Ethyl o-toluidine N-Ethyl TO-toluidine N-Ethyl p-toluidine A -Methyl a-naphthylamine A -Methyl p-naphthylanaine A -Phenyl- a-naphthylanaine Af-Phenyl- p-naphthylamine... 

CAS 99-97-8 EINECS/ELINCS 202-805-4 Synonyms Benzenamine, N,N,4-trimethyl- 4-Dimethylaminotoluene Dim-ethyl-p-toluidine DMPT p-Toluidine, N,N-dimethyl- N,N,4-Trimethylaniline p,N,N-Trimethylaniline Empirical C9H13N Formula CH,(C6H4N(CH3)2... 

Ethyl p-toluenesulfonate Bretylium tosylate N-ethyl o-toluidine Crotamiton Ethyl undecylenate lophendylate Ethyl urethane Mebuta mate 170 -Ethynyl estradiol Quinestrol... 

Trifluralin (2,6-dinitro-N, N-di-n-propyl-a,a,a-trifluoro-p-toluidine) and benefin (N-(n-butyl)-N-ethyl-2, 6-dinitro-a,a,a-trifluoro-p-toluidine)... 

Materials. Methylene 4,4 -diphenyldiisocyanate (MDI, Mobay) was recrystallized from cyclohexane. Toluenediisocyanate (TDI— represents mixture of 2,4- and 2,6-isomers in 80/20 ratio), p-toluidine (Aldrich) and aniline (Aldrich) were purified by vacuum distillation before use. Diphenylmethane, tert-butyl peroxide (TBP), 4-bromoaniline, butyl lithium in hexane, and ethyl chloroformate, were obtained from Aldrich and used as received. Spectrograde tetrahydrofuran (THF) and benzene from Burdick and Jackson were used as received. Poly(tetramethylene ether glycol) with MW 1000 was obtained from polysciences and dehydrated under a rough vacuum at 50 °C for 24 h. 

Photolytic. Irradiation of trifluralin in hexane by laboratory light produced a,a,a-trifluoro-2,6-dinitro-A-propyl-jo-toluidine and a,a,a-trifluoro-2,6-dinitro-p-toluidine. The sunlight irradiation of trifluralin in water yielded a,a,a-trifluoro-A, 7 -dipropyl-5-nitrotoluene-3,4-diamine, a,a,a-trifluoro-A/ ,A/ -dipropyltoluene-3,4,5-triamine, 2-ethyl-7-nitro-5-(trifluoromethyl)benzimidazole, 2,3-dihydroxy-2-ethyl-7-nitro-l-propyl-5-(trifluoromethyl)benzimidazoline, and 2-ethyl-7-nitro-5-(trifluoromethyl)benzimidazole. 2-Amino-6-nitro-a,a,a-trifluoro-p-toluidine and 2-ethyl-5-nitro-7-(trifluoromethyl)benzimidazole also were reported as major products under acidic and basic conditions, respectively (Crosby and Leitis, 1973). In a later study, Leitis and Crosby (1974) reported that trifluralin in aqueous solutions was very unstable to sunlight, especially in the presence of methanol. The photodecomposition of trifluralin involved oxidative TV-dealkylation, nitro reduction, and reductive cyclization. The principal photodecomposition products of trifluralin were 2-amino-6-nitro-a,a,a-trifluoro-jo-toluidine, 2-ethyl-7-nitro-5-(trifluoromethyl)benzimida-zole 3-oxide, 2,3-dihydroxy-2-ethyl-7-nitro-l-propyl-5-(trifluoromethyl)benzimidazole, and two azoxybenzenes. Under alkaline conditions, the principal photodecomposition product was 2-ethyl-7-nitro-5-(trifluoromethyl)-benzimidazole (Leitis and Crosby, 1974). 

A reactor was charged with the step 3 product (88 mmol), p-toluidine (88 mmol), and copper chloride (22 mmol) and then stirred for 5 hours at 200°C. It was cooled to ambient temperature and then dissolved in CHCI3 and washed several times with 5% hydrochloric acid, water, and then dried with MgSOzt- Thereafter the mixture was concentrated, the residue purified by recrystallization in ethyl acetate, and... 

Substrate products can be classified as either soluble or precipitating. Soluble peroxidase substrates include o-phenylenediamine, which is converted into a yellow product 2,2 -azino-(3-ethyl)-benzothiazoline-sulfonic acid, which is converted into a green product and tetramethylbenzidine, which is converted into a blue product. Precipitating substrates for peroxidase include 4-chloronaphthol, which yields a blue precipitate and aminoethylcarbizole, which forms a red precipitate. Alkaline phosphatase is most frequently used with p-nitrophenyl phosphate to give a yellow-orange soluble product, or with 5-bromo-4-chloro-3-indo-lyl-phosphate p-toluidine salt to yield an insoluble blue product. 

N, N-DimethyI-2,5-dinitro-p-toluidine, red-golden shiny pltlts (from ale), mp 103—04° readily sol in eth, chlf, ethyl acetate, hot ale hot petr eth si sol in cold ale cold petr eth was prepd by nitrating 2-nitro-4-dimethylaminotoluene with a soln of nitric-sulfuric acid and pouring into w (Ref 2, pp 1009 442)... 

Gomberg and Pemert4 recommended the use of the sodium diazotates for the preparation of biaryls from aniline and from p-toluidine and the normal diazo method for negatively substituted amines such as the bromo- and nitro-anilines. Grieve and Hey 7 found little difference in the yields of biaryls obtained by the two procedures when they coupled diazotized aniline with six different components benzene, toluene, m-xylene, chlorobenzene, nitrobenzene, and ethyl benzoate. Where it is applicable, this modification offers the advantage that the dropwise addition of alkali is eliminated. 

Chemical Name AR>utyl-V-ethyl-a,a,a-trifluoro-2,6-dinitro-p-toluidine... 

The iV-methylamine (160) (R = Me) gives a complex mixture of products when treated under the same conditions.186 It was shown subsequently that prior reduction of the anils used as starting materials is, in fact, unnecessary since in the presence of potassamide in liquid ammonia (o-chlorobenzylidene)aniline forms phenanthridine in excellent yield, and the analogous anils from p-toluidine and a-naphthylamine undergo ring closure under similar conditions. In view of the known trans geometry of the anils and the unlikelihood of trans-cis equilibration under these conditions this reaction deserves further study.187 Potassamide in liquid ammonia also converts 2-bromo-iV-ethyl-3 -hydroxybenzanilide (162) into a mixture of iV-ethyl-3-(164) and N-ethyl-1 -hydroxyphenanthridone (165), probably via the aryne (163).188... 

The liquid phase of the dispersions contained, by weight, 99% methyl methacrylate, 0.5% distilled dimethyl-p-toluidine, and 0.5% ultraviolet absorber. Matrices used for volume concentration effects contained 5% ethylene dimethacrylate and 10% methyl methacrylate-ethyl methacrylate copolymer with methyl methacrylate monomer reduced to 84%. Matrices containing 5% additives (described above) contained 15% triethylene glycol dimethacrylate with methyl methacrylate reduced to 79%. 

The same authors also introduced a r scale of solvent dipolarity/polarizability [84a]. This n scale is so named because it is derived from solvent effects on the n n electronic transitions of a selection of seven positively solvatochromic nitroaromatics of the type D-C6H4-A, where D and A stand for electron-donor e.g. NMe2) and electron-acceptor e.g. NO2) groups, respectively 4-nitroanisole, A,A-diethyl-3-nitroaniline, 4-methoxy-/ -nitrostyrene, 1-ethyl-4-nitrobenzene, A-methyl-2-nitro-p-toluidine, N,N-diethyl-4-nitroaniline, and 4-(dimethylamino)benzophenone. Given a solvatochromic indicator compound, the n value for a solvent S was defined according to Eq. (7-32) ... 

C6H140 ethyl butyl ether 628-81-9 m benzene 1.220 1 10957 C7H9N p-toluidine 106-49-0 in benzene 1.310 1... 

Fierz-David and Ziegler (301) first applied this method to azo compounds. Ethyl acetoacetate and various aromatic amines (aniline, o- and p-toluidines, m-xylidine, o-anisidine, and chloroanilines) were convereted to acetoacetanilides and then coupled with diazotized sulfanilic acid. The azo dyes (38) were reduced with stannous chloride in hydrochloric acid to the corresponding aminoaceto-acetanilides (39), which in alkali formed the dihydropyrazines (40). Catalytic reduction of o-hydroxyphenylglyoxal phenylhydrazone in acetic acid over palladium has been shown also to give 2,5-bis(o-hydroxyphenyl)pyrazine (302). Reduction of chemical means has been shown to give... 

Acetoxymercuri dimethyl-p-toluidine crystallises from boiling benzene in colourless, slender, glistening needles, M.pt. 131 5° C., insoluble in water, more soluble in methyl than ethyl alcohol. 

Mercuri-bis-(dimethyl-p-toluidine) is obtained when the above hjKlrate is treated with concentrated sodium thiosulphate, and when bromo-dimethyl-p-toluidine is heated with 1 5 per cent, sodium amalgam for forty-eight hours at 120° to 125° C., a little ethyl acetate being used as catalyst. It crystallises in colourless, glistening plates, M.pt. k)° C., sliglitly soluble in benzene. 

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