Ethyl 2-methoxy-4-hydroxy-6-methylbenzoate

Preparation by reaction of ethyl 2-hydroxy-4-methoxy-6-methylbenzoate (m.p. 73-74°) with sodium methyl-sulfinylmethide, itself obtained from DMSO and sodium hydride (85%) [5587]. 

Ethyl isoeverninate. Ethyl 2-methoxy-4-hydroxy-6-methylbenzoate... 

Ethyl 2-methoxy-4-hydroxy-5-formyl-6-methylbenzoate (2-Methoxy-4-hydroxy-5-formyl-6-methylbenzoesaureethylester)... 

As a typical example of tridepside synthesis, the preparation of 5-0-methylhiascic acid (227) is depicted in Scheme 35 122). Persulfate oxidation of ethyl 4-benzyloxy-2-hydroxy-6-methylbenzoate (273) in potassium hydroxide solution gave the corresponding 5-hydroxy derivative (274) from which 2,4-dibenzyloxy-5-methoxy-6-methylbenzoic acid (275) was prepared. Condensation of this acid with benzyl lecanorate (276) gave the... 

Staggered configurations have also been observed for the tricarbonyl chromium complexes of phenanthrene 294, 295), 9,10-dihydro-phenanthrene 293, 295), anthracene 202), naphthalene 262), and 1-aminonaphthalene 58). The eclipsed configuration has been observed for the tricarbonyl complexes of anisole (57, 229), toluidine 60, 61), methylbenzoate (59), o-methoxyacetylbenzene, o-hydroxyacetylbenzene 101), 2-methoxy-[l-hydroxy-ethyl]benzene (99), and 2-methyl-[l-hydroxy-l-phenylpropyl]benzene (97). It is apparent that the orientation of the chromium tricarbonyl moiety is in many cases controlled by the substituents on the ring to which it is coordinated, and this has been attributed to mesomeric electron repulsion or withdrawal by the substituents 374). 

Ethyl 3-chloroeveminate, Ethyl 2-hydroxy-3-chloro-4-methoxy-6-methylbenzoate... 

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