Ethanethiols, 2-

Deoxy-D-araMno-hexose (0.8 g, 4.88 mmol) is dissolved in concentrated hydrochloric acid (5 mL) and ethanethiol (2 mL), and the mixture is shaken overnight at room temperature. Ethanol (50 mL) is added, and the solution is neutralized with lead carbonate. Insoluble salts are filtered and washed with ethanol (20 mL). Evaporation affords a syrup (0.5 g, 40%), which crystallizes slowly and can be recrystallized from acetone-ether mp 132°C, [ojp -8.8° (c 23, methanol). A fader procedure, employing essentially the same conditions, reports a yield of 69% [18]. 

SYNS ISOPROPYL mercaptan (DOT) isoprop-YLTHIOL 2-MERCAPTOPROPANE 1-METHYL-ETHANETHIOL 2-PROPANETHIOL 2-PROPYL MERCAPTAN... 

SYNS EMERY 5791 1-ETHANOL-2-THIOL 2-HYDROXY-l-ETHANETHIOL 2-HYDROXYETHYL MERCAPTAN 2-ME MERCAPTOETHANOL P-MERCAPTOETHANOL MONOTfflOETHYLENE-GLYCOL 2-THIOETHANOL TfflOGLYCOL (DOT)... 

Synonyms 2-ME Mercaptoethanol l-Ethanol-2-thiol 2-Hydroxy-1-ethanethiol 2-Hydroxyethyl mercaptan Monothioethyleneglycol 2-Thioetha-nol Thioglycol... 

A solution of methyl 4-chloro-3,3,4-trifluorocyclobut-l-enecarboxylatc (12 2.0 g, 10 mmol) in F.t20 (20 mL) was added dropwisc to a mixture of KOH (2.0 g) and ethanethiol (2.0 g). The mixture was stirred for 25 h. washed with H2C) (5()niL). and extracted with Et20 (4x20mL). The combined layers were dried and the solvent was evaporated to give a residue which was distilled in a Kugelrohr apparatus yield 2.67g (81 %) bp 130 C 0.05 Torr. 

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