Ethanethiol chemical structure

FIGURE 55.10. The chemical structures of 2-(dieth-ylamino)ethanethiol and 2-(dimethylamino)ethanethiol. 

Over the years, several techniques have been developed to elucidate the structure of a new lantibiotic. The extensive post-translational modifications limit Edman degradation to a stretch of amino acids from the N-terminus to the first modification. Various chemical derivatization techniques have been used to allow continuation of the sequence and to reveal the position of the posttranslationaUy modified residues. Originally, these techniques relied on treatment with ethanethiol under highly basic conditions that result in elimination reactions of the thioethers... 

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