Estrogen Receptors and Estrogenicity

TABLE 23.1. Summary of Experimental Evidence for Functional Effects of Isoflavones. 

Cardiovascular Risk biomarkers used as outcome variabies instead of disease cardirtvascuiar events  

Soy foods/protein reduced LDL-C and increased HDL-C in large amounts but isoflavone supplementation ineffective. Other components of soy foods responsible  

Weak evidence that soy isoflavones may reduce systolic blood pressure. 

Inconsistent results from chronic inten/ention studies, possibly related to the faot that arterial measurements often made when circulating isoflavone levels are low isoflavones may have acute effects on nitric oxide production. Antioxidant action  

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Gaubert cm, Carriero R and Shyamaia G (1986) Relationships between mammary estrogen receptor and estrogenic sensitivity. Molecular properties of cytoplasmic receptor and its binding to deoxyribonucleic aced. Endocrinology 118 1504—1512. 

Henricks, D.M. Harris, R.B., Jr (1978). Cytoplasmic estrogen receptors and estrogen concentrations in bovine uterine endometrium. Endocrinology, 93, 176-185. 

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