Epigallocatechin gallate structure

Three-dimensional structure and dynamics of wine tannin-saliva protein complexes. A multitechnique approach. Biochemistry 42 10385-10395 Haslam E (1974) Polyphenol-protein interactions. Biochem J 139 285 Jobstl E, Howse JR, Fairclough JPA, Williamson MP (2006) Noncovalent cross-linking of casein by epigallocatechin gallate characterized by single molecule force microscopy. J Agric Food Chem 54 4077 081... 

The inherent difficulties in the characterization, distribution, and localization of flavonoids within the body pose a major hurdle when attempting to investigate mechanisms of flavonoid bioactivity in vivo. Compounds reported to localize within brain structures include epigallocatechin gallate [21], a major polyphe-nolic in tea and to a lesser degree in wine, and the citrus flavonoids hesperetin... 

The concentration of 4, 4"-di-0-methyl-epigallocatechin gallate was about 15% that of unmethylated epigallocatechin gallate in human plasma. It is likely that the gallated flavan-3-ols produce numerous combinations of conjugated metabolites. The structures of the predominant forms of these metabolites in plasma after green tea consumption need to be determined. 

Each of the four theaflavins theoretically are derived from the reactions the quinones of epicatechin or its gallate with those of epigallocatechin or its gallate has been identified in black tea and its structure authenticated.50... 

Suzuki, M., Sano, M., Yoshida, R., Degawa, M., Miyase, T., and Maeda-Yamamoto, M., Epimerization of tea catechins and 0-methylated derivatives of (—)-epigallocatechin-3-0-gallate relationship between epimerization and chemical structure, J. Agric. Food Chem., 51, 510, 2003. 

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