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Epidermal growth factor receptor naming

Herceptin is the trade name given to one such antibody-based cancer therapy product (Table 8). It is a humanized niAb with binding specificity for the human epidermal growth factor receptor 2 (HER2), which is overexpressed on the surface of 25-30% of metastatic breast cancers. HER2 overexpression induces abnormal proliferation of cells (see also Part I, Chapter 5). The niAb binds specifically to the... [Pg.36]

Abbreviations and trivial names used are RME, receptor-mediated endocytosis LDL, low density lipoprotein EGF. epidermal growth factor SDS, sodium dodecyl sulfate LH, luteinizing hormone hCG, human chorionic gonadotropin and G protein, guanine nucleotide binding protein. [Pg.133]

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See also in sourсe #XX -- [ Pg.4 ]

See also in sourсe #XX -- [ Pg.4 ]



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