Enzymes advantages over synthetic catalysts

Chemists now use water as a solvent for synthetic reactions, which takes advantage of the selectivities that the hydrophobic effect can induce (4). Many enzyme mimics (vide infra) also use water as the medium to promote substrate binding into the catalyst. Of course, water as a solvent also has important environmental advantages over volatile organic solvents. It remains to be seen how much impact the special properties of water as a solvent wiU have within chemical synthesis and manufacturing. 

A simple microfluidic reactor system He et al. [124] for the effective synthesis of enzyme-functionalized nanoparticles offers many advantages over batch reactirais, including excelloit enzyme efficiencies. Better control of the process parameters in the microfluidic reactor system ovct batch-based methodologies enables the production of silica nanoparticles with the optimum size for efficient enzyme immobilization with long-term stability. The synthetic approach used glucose oxidase and two different nucleation catalysts of similar molecular mass the natural R5 peptide, and PEI polymer... 

The last few years have witnessed spectacular advancement in chiral Bronsted acid catalysis. Thiourea and phosphoric acids, in particular, have emerged as novel chiral catalysts of choice in a number of synthetic reactions. A number of chiral alcohols and nitrogen containing materials have been obtained with excellent optical purity in a simple protocol. The scope of the catalysts will be expanded by further study. They are considered to be artificial enzymes. One of the advantages of chiral Bronsted acid over chiral Lewis acid is the stability toward moisture and... 

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