Enzyme-analogue built polymers

Wulff G, Sarhan A, Zabrocki. K. Enzyme-analogue built polymers and their use for the resolution of racemates. Tetrahedron Lett 1973 44 4329-4332. 

Molecular imprinting in synthetic polymers was reported for the first time in 1972 [1--4]. The initial idea was to obtain in the polymer highly specific binding clefts with a predetermined size, shape and three-dimensional arrangement of functional groups. Later on, further experiments demonstrated that such functionalised cavities could be tailored to mimic the active sites of enzymes ( enzyme analogue built polymer ). 

To fulfill these prerequisites, we have introduced a novel strategy for obtaining enzyme-analogue built polymers [4,5]. For this, a cross-linked polymer is formed... 

Wulff, G. Vietmeier, J. Poll, H.-G. Enzyme-analogue built polymers, 22. Influence of the nature of the crosslinking agent on the performance of imprinted polymers in racemic resolution. Makromol. Chem. 1987, 188, 731-740. 

Wulff, G. Lohmar, E. Enzyme-analogue built polymers. Specific binding effects in chiral microcavities of cross linked polymers. Isr. J. Chem. 1979,18, 279-284. 

Wulff, G. Best, W. Akelah, A. Enzyme-analogue built polymers, 17. Investigations on the racemic resolution of amino adds. React. Polym. Ion Exch. Sorbents 1984, 2, 167 174. 

Wulff, G. Grobe-Einsler, R. Vesper, W. Sarhan, A. Enzyme-analogue built polymers, 5, On the specificity distribution of chiral cavities prepared in synthetic polymers. Mark-romol. Chem. 1977, 178, 2817-2825. 

Wulff, G. Oberkobusch, D. Minarik, M. Enzyme-analogue built polymers, 18. Chiral cavities in polymer layers coated on wide-pore silica. React Polym. 1985, 3, 261-275. 

Wulff G, Haarer J. Enzyme-analogue built polymers. The preparation of defined chiral cavities for the racemic resolution of free sugars. Makromol Chem.1991 192 1329-1338. 

G. Wulff and J. Vietmeier, Enzyme-analogue built polymers, Enantioselective synthesis of amino acids using polymers possessing chiral cavities obtained by an imprinting procedure with template molecules, Makromol. Chem., 190 (7) 1727-1735,1989. 

G. Wulff, W. Best and A. Akelah, Enzyme-analogue built polymers 17. Investigations on the racemic resolution of aminoacids. React Polym., 2 (3) 167-174,1984. 

Wulff, G, Wesper, R., Grobe-Einsler, R. and Sarchan, A., Enzyme-analogue built polymers (4) on the synthesis of polymers containing chiral cavities and... 

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