Enzyme Activity Is Regulated by Interaction with Regulatory Factors

Enzyme Activity Is Regulated by Interaction with Regulatory Factors 

The most common way of regulating metabolic activity is by direct control of enzyme activity. Enzyme activities are usually regulated by noncovalent interaction with small-molecule regulatory factors (see chapter 9) or by a reversible covalent modification, such as phosphorylation or 

Three patterns for end-product inhibition. In end-product inhibition the first reaction in the pathway (a) or the first reactions after a branchpoint (b) are inhibited by the specific end products (c). Sometimes the first step in the overall pathway is inhibited by the end products from both branchpoints. 

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