Environmental exposure regulatory approaches

Bigelow P., Moore D., Yassi A. (2004) Assessing the health implications for healthcare workers of regulatory changes eliminating locally developed occupational exposure limits in favor of TLVs An evidence-based bipartite approach. International Journal of Occupational and Environmental Health 10(4) 433—444. 

As can be expected, some chemicals are data-rich while others are data-poor. Often they are data-poor, especially for chemical mixtures where the data may be adequate, barely adequate or nonexistent for a specific mixture. Thus limited methods are available for the toxicity assessment of chemical mixtures [1,9]. Even though there are various uncertainties and assumptions embedded in these methods, the following three approaches have gained acceptance by the regulatory agencies and the regulated community for risk assessment of mixtures of industrial, occupational, and environmental chemicals. The method employed is on a case-by-case basis, it depends on the exposure scenario and the quality of available data on exposure and toxicity. 

Natural attenuation (NA) refers to the reduction of contaminant concentrations in environmental media by processes such as dilution, dispersion, sorption, volatilization, and biotic or abiotic transformations. As a passive remediation approach, NA is mostly applied in connection with organic contaminants which migrate from the source in groundwater. Naturally attenuating contaminant plumes show a decline in the dissolved contaminant mass as a function of time, and a decline in contaminant concentrations downgradient from the source. Before potential receptor exposure points are reached, natural attenuation is expected to reduce dissolved contaminant concentrations below regulatory standards (Wiedeme-ier et al. 1999). 

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