Enteric coating Heidelberg capsule

Figure 8 Schematic for attachment of the enteric-coated tablet to the Heidelberg pH detector capsule (From Ref. 58).

The relationship between gastric residence time (GRT) and the variability in aspirin absorption from enteric-coated tablets has also been evaluated with the Heidelberg capsule [59], The study design was a single dose crossover study with men and women, fasted and fed. In addition to pH monitoring, plasma concentrations of salicylic acid and salicyluric acid in plasma and urine were measured. GRT was significantly delayed in the fed state, and women had longer GRT compared with men. 

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See also in sourсe #XX -- [ ]

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