Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Permeability, enhanced skin, transdermal drug delivery

Transdermal Drug Delivery System with Enhanced Skin Permeability... [Pg.281]

A new generation of transdermal drug delivery (TDD) system was developed to contain one or more skin permeation enhancers in the surface adhesive coating layers. This TDD system has been found, experimentally, to release the enhancers to the surface of stratum corneum to modify the skin s barrier properties, prior to the controlled delivery of the active drug. The extent of enhancement in skin permeability appears to be dependent upon the chemical structure of drug to be delivered transdermally as well as the type and the concentration of enhancer used. The mechanism of skin permeation enhancement have been explored and are analyzed in this report. [Pg.281]

Xu,P, and Chien, Y. W. (1991), Enhanced skin permeability for transdermal drug delivery Physiopathological and physicochemical considerations, Crit. Rev. Ther. Drug Carrier Syst., 8(3), 211-236. [Pg.806]

Because of the low permeability of the skin to many drugs, trans-dermal delivery has limited applications. The low permeability is attributed primarily to the stratum comeum, the outermost skin layer which consists of flat, dead cells filled with keratin fibers surrounded by lipid bilayers. One common method of increasing the passive transdermal diffusional drug flux involves pretreating the skin with a skin permeation enhancer. [Pg.250]

See other pages where Permeability, enhanced skin, transdermal drug delivery is mentioned: [Pg.199]    [Pg.564]    [Pg.373]    [Pg.77]    [Pg.283]    [Pg.292]    [Pg.172]    [Pg.1]    [Pg.260]    [Pg.261]    [Pg.262]    [Pg.124]    [Pg.214]    [Pg.1059]    [Pg.574]    [Pg.443]    [Pg.464]    [Pg.250]    [Pg.2681]    [Pg.235]    [Pg.223]    [Pg.120]    [Pg.120]    [Pg.827]    [Pg.280]    [Pg.338]    [Pg.477]    [Pg.172]    [Pg.996]    [Pg.2741]    [Pg.3828]    [Pg.3851]    [Pg.119]    [Pg.311]    [Pg.832]    [Pg.228]    [Pg.251]    [Pg.128]    [Pg.2701]    [Pg.274]    [Pg.564]    [Pg.393]   
See also in sourсe #XX -- [ Pg.281 , Pg.282 , Pg.283 , Pg.284 , Pg.285 , Pg.286 , Pg.287 , Pg.288 , Pg.289 , Pg.290 , Pg.291 , Pg.292 , Pg.293 , Pg.294 , Pg.295 , Pg.296 , Pg.297 , Pg.298 ]



SEARCH



Drug permeability

Enhanced skin permeability, transdermal drug

Enhancement drugs

Permeability enhancers

Permeability, enhanced

Permeability, enhanced skin, transdermal

Skin permeability

Transdermal

Transdermal drug delivery

Transdermal drugs

© 2024 chempedia.info