Enfuvirtide adverse effects

The most common adverse effects associated with enfuvirtide therapy are local injection site reactions. Hypersensitivity reactions may rarely occur, are of varying severity, and may recur on rechallenge. Eosinophilia has also been noted. In one prospective clinical trial, an increased rate of bacterial pneumonia was noted in patients receiving enfuvirtide. No interactions have been identified that would require the alteration of the dosage of other antiretroviral drugs. 

Adverse Effects. Enfuvirtide must be administered by subcutaneous injection, and local pain and irritation occurs at the injection site in most patients. Other common side effects include peripheral neuropathy and immune complex reactions that can lead to serious problems including respiratory distress syndrome, kidney dysfunction, and possibly Guillain-Barre syndrome. 

The most prominent adverse effects of enfuvirtide are injection-site reactions. In 98% of patients, one or more local side effects including pain, erythema, and induration at the site of injection are seen 80% of patients develop... 

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