Endogenous oxides

Ames, B.N. (1989). Endogenous oxidative DNA damage, aging and cancer. Free Rad. Res. Commun. 7, 121-127. 

Fraga, C.G., Motchnik, P.A., Shigenaga, M.K., Helbock, H.J., Jacob, RA. and Ames, B.N. (1991). Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc. Natl Acad. Sci. USA 88, 11006-11033. 

Naudi, A., Caro, P., Jove, M., Gomez, J., Boada, J., Ayala, V., Portero-Otin, M., Barja, G., and Pamplona, R. (2007). Methionine restriction decreases endogenous oxidative damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain. Rejuvenation Res. 10,473M84. 

Wagner JR, Decarroz C, Berger M, Cadet J (1999) Hydroxyl-radical-induced decomposition of 2 -de-oxycytidine in aerated solutions. J Am Chem Soc 121 4101-4110 Wagner JR, Hu C-C, Ames BN (2004) Endogeneous oxidative damage of deoxycytidine in DNA. Proc Natl Acad Sci USA 89 3380-3384... 

Wagner JR, Hu C-C, Ames BN (2004) Endogeneous oxidative damage of deoxycytidine in DNA. Proc Nat Acad Sci USA 89 3380-3384... 

The loss of control of endogenous oxidative events in the use of molecular oxygen by the cell is the major factor in oxidative stress injury. Such a process, which is known as chemical-induced oxidative stress, may occur to an extent that ranges from a minor to a major contribution to overall toxicity. For example, chemicals that are known to undergo redox cycling cause exogenous oxidative stress to such a degree that they play a major role in chemically induced cell injury. In addition, some of these chemicals are known to form adducts with cellular constituents, particularly... 

Until recently, methods for determination of both activities were essentially of two types the determination of UDP formation enzymatically by a spectrophotometric method and the determination of the incorporation of UDP[U- C] galactose into [ C] lactose. The first type is limited to purified systems, since crude systems catalyze the endogenous oxidation of NADH (Brodbeck and Ebner, 1966). 

Pool-Zobel, B.L., Bnb, A., Schroder, N., and Rechkemmer, G., Anthocyanins are potent antioxidants in model systems bnt do not rednce endogenous oxidative DNA damage in human colon cells, Eur. J. Nutr., 38, 227-234, 1999. 

H exachl orcycl ohexane chronic 1 Endogenous oxidative stress 2... 

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