Embden-Meyerhof-Parnas

A major route of breakdown of carbohydrates is the Embden-Meyerhof-Parnas pathway, often referred to simply as glycolysis. It is indicated on the left side of Fig. 10-1 and in more detail in Figs. 

Figure 10-3 Coupling of the reactions of glycolysis with formation of lactic acid and ethanol in fermentations. Steps a to g describe the Embden-Meyerhof-Parnas pathway. Generation of 2 ATP in step b can provide all of the cell s energy.

Figure 17-9 Reaction sequences in fermentation based on the Embden-Meyerhof-Parnas pathway. Oxidation steps (producing NADH + H+) are marked "O" reduction steps (using NADH + H+) are marked "R."...

The biochemistry of alcoholic fermentation involves a series of internal enzyme-mediated oxidation-reduction reactions m which glucose is degraded via the Embden-Meyerhof-Parnas pathway See also Carbohydrates and Glycolysis. 

The sequence of biochemical steps by which glucose is degraded to pyruvic acid is called glycolysis or the Embden-Meyerhof-Parnas (EMP) Pathway, and is shown... 

Fio. 5.18. The Embden-Meyerhof-Parnas pathway. The six carbon substrate, (glucose) yields two three carbon intermediates to produce two moles of pyruvate... 

Fig. 4. Carbon transitions in the Embden-Meyerhof-Parnas (EMP) and the Entner-Doudoroff (ED) pathway. In the EMP pathway, Cl-labeled glucose is converted into 50% unlabeled and 50% C3-labeled pyruvate, while the ED pathway produces 50% unlabeled and 50% Cl-labeled pyruvate...

The data show that SSHB increased the root dry matter in the same way it did in the other experiments. Simultaneously, we observed an increase in leaf length and leaf area which corresponded with an increase in invertase activity. The higher enzyme activity appeared to be the key to the whole problem. It is well known that acid invertase splits the disaccharide sucrose so that the two monosaccharides formed from it can become building stones for additional leaf substances. That is, glucose is recycled through the Embden-Meyerhof-Parnas pathway. Likewise, fructose is readily available for conversion into fructose 1,6-diphosphate. Subsequently, more leaf area arises which is able to produce more assimilates. The consequence is an increased yield. Thus, photosynthetic efficiency increases considerably. 

S ATP + D-allose <1> (<1> first step of Embden-Meyerhof-Parnas pathway... 

Figure 6.1 Carbon core metabolism of Corynebacterium glutamicum comprising the major catabolic routes of pentose phosphate pathway and Embden-Meyerhof-Parnas pathway, tricarboxylic acid cycle, glyoxylate shunt, and anaplerotic reactions. The relevance of the individual pathways and carbon building blocks for biosynthesis of the broad product...

Elucidation of the metabolic pathway repertoire of C, glutamicum was initiated soon after its discovery [4-6], related to the high importance of the central metabolism for amino acid fermentation. Evidence on the presence of the major catabolic routes, such as the Embden-Meyerhof-Parnas (EMP) pathway, the pentose phosphate (PP) pathway, the tricarboxylic acid (TCA) cycle, and the glyoxylate shunt had already been provided by the end of the 1950s [4, 5, 7] (Figure 6.1). However, it took more than 30 years for a more detailed resolution of the central metabolic network mainly related to the complex structure of the phosphoenolpyruvate/pyruvate - oxaloacetate/malate node [8-11]. Altogether,... 

Glutamic acid formation from glucose by bacteria. I. Enzymes of the Embden-Meyerhof-Parnas pathway, the Krebs cycle, and the glyoxylate bypass in cell extracts of Brevibac-terium flavum No. 2247. J. Biochem.,... 

Similarly to other rhizosphere symbiotic bacteria, P. putida KT2440 lacks the enzyme 6-phophofructokinase (Pfk) [18] and therefore it exhibits a nonfunctional glycolytic Embden-Meyerhof-Parnas (EMP) pathway (Eigure 8.1). Accordingly,... 

I Embden-Meyerhof-Parnas pathw I Pentose phosphate pathway I Entner-Doudoroff pathw ... 

Figure 8.4 Biosynthetic potentiai of Pseudomonas putida. Extended carbon core metabolism of Pseudomonas putida KT2440 including the major catabolic routes of Entner-Doudoroff pathway, Embden-Meyerhof-Parnas pathway, pentose phosphate pathway, tricarboxylic acid cycle, glyoxylate shunt, anaplerotic reactions, fatty acid de novo biosynthesis, p-oxidation of fatty acids, as well as the convergent -ketoadipate pathway for catabolism of aromatics. Known pathways for respective precursor supply for the broad product spectrum of P. putida KT2440 are indicated by light red arrows. Natural products and substrates are highlighted in black, heterologous products and substrates In red.

Nikel, P.I., Chavarria, M., Fuhrer, T., Sauer, U., and de Lorenzo, V. (2015) Pseudomonas putida KT2440 metabolizes glucose through a cycle formed by enzymes of the Entner-DoudorofF, Embden-Meyerhof-Parnas, and pentose phosphate pathways. J. Biol Chem., 290 (43), 25920-25932. 

Embden-Meyerhof-Parnas pathway 650 photobioreactors 589,628 endoplasmic reticulum (ER) 648, 701 endoplasmic reticulum associated degradation (ERAD) 701 enzymes 677,703... 

The principal pathway for the fermentation of glucose and fructose is the Embden-Meyerhof-Parnas route (alternatively named EMP or glycolytic sequence). Wort sucrose is hydrolysed extracellularly and maltose and maltotriose intracellularly. Intracellular storage carbohydrates such as glycogen and trehalose may also serve as sources of intracellular monosaccharide. 

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