Ellman, Jonathan

Earle, Martyn, 21 Eberlin, Marcos N., 202 Ellman, Jonathan, 122 Enders, Dieter, 185 Ermolenko, Mikhail S., 186 Estevez, Ramon J., 9 Evans, P. Andrew, 140... 

Sean H. Wiedemann, Jonathan A. Ellman, and Robert C. Bergman... 

This issue highlights the characterization difference between parallel synthesis and combinatorial synthesis. Parallel synthesis is automated traditional organic chemistry. Each compound is made in a separate reactor, purified and characterized. There is no excuse for not fully characterizing compounds made by parallel synthesis. Jonathan Ellman s laboratory at UC Berkeley has been a pioneering academic center for solid-phase chemistry development. His philosophy is to synthesize libraries of discrete compounds in a spatially separate fashion, rather than libraries of compound mixtures, to allow for rigorous analytical characterization [48,49],... 

Jennifer L. Hanis, Bradley J. Backes, Francesco Leonetti, Sami Mahrus, Jonathan A. Ellman, Charles S. Craik, Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries. Proceedings of the National Academy of Sciences USA, 97 (2000), 7754-7759. 

The C-H bond does not have to be attached to an aromatic ring. Robert Bergman and Jonathan Ellman of the University of California at Berkeley have reported (Organic Lett. 2004,6, 1685) that a Rh catalyst will activate 4 to add to simple alkenes such as 3 in a reductive sense, to give 5. 

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