Elemane

Additional examples of elemanolides from a variety of plant sources include disynaphiolide (586),229 a series of 8-epizinamultifluoride esters (587),231 iso-arbutifolin (588) and its 11,13-dihydro derivative,234 and (589 R = COC(CH2)Me or R = Tig).266 

A full report on the preparation of the photo-adduct (590) from methylcyclo-butene and (—)-piperitone and its thermal conversion into the various shyobunones (591) and related sesquiterpenoids has appeared.267 Another synthesis of the cytotoxic compound (+)-deoxyvernolepin (592) Starting from a-santonin has been recorded.268 

Occasionally co-metabolites are included in these structures for convenient referencing. 

Samek and J. Harmatha, Collect. Czech. Chem. Commun., 1978, 43, 2779. 

Renold, G. Ohloff, and T. Norin, Helv. Chim. Acta, 1979,62, 985. 

Reagents i, Base ii, MejSiCl iii, room temp. iv, H2O v, SOCI2 vi, SnCl4 vii, DBN viii, 

New elemanolides include 8a-H-secoeudesmanolide (424), secoeudes-manolide (425)/ the two dihydromelitensin derivatives (426), various zinamultifloride esters (427) and the corresponding epoxy-compounds (428), and 

Although the synthetic challenge of vernolepin (430) and vernomenin (431) has been met by a number of groups, several interesting papers in this area have 

A full report on the identification of the six related lactones callitrin (458), callitrisin (459), dihydrocallitrisin (460), columellarin (461), dihydrocolumellarin 

Geijerone (465) and y-elemene (466) have both been synthesized by reductive fragmentation of the keto-mesylate (468) which is readily available from the Wieland-Miescher ketone (467). Another synthesis of the key vemolepin 

Fujimoto, H. Miura, T. Shimizu, and T. Tatsuna, Tetrahedron Lett., 1980, 21, 3409 H. Miura, 

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The interaction between the dispersed-phase elements at high volume fractions has an impact on breakup and aggregation, which is not well understood. For example, Elemans et al. (1997) found that when closely spaced stationary threads break by the growth of capillary instabilities, the disturbances on adjacent threads are half a wavelength out of phase (Fig. 43), and the rate of growth of the instability is smaller. Such interaction effects may have practical applications, for example, in the formation of monodisperse emulsions (Mason and Bibette, 1996). 

Fig. 43. Capillary breakup of closely spaced molten nylon-6 threads in molten polystyrene. Photograhs at different times are shown (frames a through f correspond to 0, 210, 270, 360, 390, and 510 s). The initial thread diameter is 70 fim (Elemans el at., 1997).

Elemans, P.H.M. and van Wunnik, J.M., The Effect of Feeding Mode on Dispersive Mixing Efficiency in Single-Screw Extrusion, Polym. Eng. Set, 41, 1099 (2001)... 

Sesquiterp. dimers elemane/eudesmane macrophyilidimer A and dimeric elemane Inula macrophylla from Uzbekistan Su 2000). 

Intramolecular sulfur ylide formation and subsequent [2,3]-sigmatropic rearrangement has been utilized in construction of ring systems, as demonstrated by the total synthesis of (+)-/3-elemenone 118 and (+)-eleman-8/ , 12-olide 117 (Scheme a-diazo (3-kcto esters 113 as the starting material, the core structure is formed... 

Johannes A.A.W. Elemans, JeroenJ.L.M. Cornelissen, Martinas C. Feiters, Alan E. Rowan, and RoelandJ.M. Nolte... 

Elemans, J.A.A.W., Bijsterveld, E.J.A., Rowan, A.E. and Nolte, R.J.M. (2000) A host-guest epoxidation catalyst with enhanced activity and stability. Chem. Commun., 2443—2444. 

Vriezema DM, Cornelias Aragones M, Elemans JAAW, Cornelissen JJLM, Rowan AE, Nolte RJM (2005) Chem Rev 105 1445... 

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