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Electrospray interface biopolymers

GC/MS with capillary columns has been the gold standard for more than 20 years, but LC/MS has become a complementary method due to the success in interface development with atmospheric pressure ionisation (API) for low molecular weight compounds and the appHcation to biopolymers. For many areas of analytical chemistry, LC/MS has become indispensible due to its advantages over GC/MS for polar and thermolabile analytes. A Hmiting factor for LC/MS has been the incompatibility between the hquid eluting from the LC and the mass spectrometer vacuum. This could be overcome in electrospray ionisation with the use of a nebuliser gas ( ion spray ) or additional heated drying gas ( turbo ion spray ) (70, 71]. Due to its high sensitivity and selectivity, APl-MS has become a standard tool for the stracture elucidation of analytes from complex mixtures. [Pg.347]

See other pages where Electrospray interface biopolymers is mentioned: [Pg.493]    [Pg.106]    [Pg.320]    [Pg.372]    [Pg.15]    [Pg.2]    [Pg.281]    [Pg.2715]    [Pg.350]    [Pg.1304]    [Pg.599]    [Pg.248]    [Pg.1417]    [Pg.1386]    [Pg.1414]   
See also in sourсe #XX -- [ Pg.141 , Pg.142 , Pg.143 , Pg.144 , Pg.145 , Pg.146 , Pg.147 , Pg.148 ]

See also in sourсe #XX -- [ Pg.141 , Pg.142 , Pg.143 , Pg.144 , Pg.145 , Pg.146 , Pg.147 , Pg.148 ]



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