Electroactive compounds amperometric sensors

Amperometric sensors for electroactive compounds Advanced sensor for hydrogen peroxide... 

Amperometric sensors for redox-inactive cations and electroactive compounds... 

AMPEROMETRIC SENSORS FOR REDOX-INACTIVE CATIONS AND ELECTROACTIVE COMPOUNDS... 

High sensitivity, selectivity, and ability to operate in turbid solutions are advantages of electrochemical biosensors. Amperometric detection is based on measuring the oxidation or reduction of an electroactive compound at a working electrode (sensor). A potentiostat is used to apply a constant potential to the working electrode with respect to a second electrode (reference electrode). A potentiostat is a simple electronic circuit that can be constructed using a battery, two operational amplifiers, and several resistors. The applied potential is an electrochemical driving force that causes the oxidation or reduction reaction. 

Different electrochemical sensors have been developed for cell concentration measurement. The most promising of these sensors are based on impedimetric measurements. A commercial version of a sensor that measures the frequency-dependent i)ermittivity is available from Aber Instruments Ltd [137-139]. Another type of electrochemical probe measures the potential changes in the cell suspension caused by the production of electroactive substances during cell growth [140-143]. To date, no on-line applications of these potentiometric sensors under real cultivation conditions have been reported. Other types of probes, such as amperometric and fuel-cell sensors, measure the current produced during the oxidation of certain compounds in the cell membrane. Mediators are often used to increase the sensitivity of the technique [143-145]. 

---