Eicosapentaenoic acid anti-inflammatory effects

Fish is the most important source of the n-3-PUFAs Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and populations consuming fish have lower heart rates. Other important parameters reported were lower blood pressure and higher HDL cholesterol. The strongest evidence for an effect of n-3-fatty acids on disease is the inverse relationship between diet, blood, and tissue levels and coronary heart disease. n-3-PUFAs prevent heart disease by preventing arrhythmias, generating prostanoids and leukotrienes with anti-inflammatory actions, and inhibiting synthesis of cytokines and mitogens that provoke inflammation and promote plaque formation. ... 

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