Effects of Ischemia on Cell Proliferation and Differentiation

SGZ (Seri et al. 2001). Our findings appear to differ from these results, and the reason could be that species variations may exist between monkeys and rodents with regard to the molecular identity of SGZ progenitors. 

In contrast to DG, no signs of neuronal production were detected in postis-chemic CA1, where despite the marked cell loss followed by a striking increase of proliferating cells, the latter were invariably of a glial phenotype. Most BrdU+ cells in monkey CA1 were microglia, as with the rodent brain (Liu et al. 2001b)  

Dentate gyrus 45%—Neural progenitors 30%—Microglia 12%—Neuronal progenitors 8%—Neurons 5%—Other 

Cornu Ammonis 80%—Microglia 15%—Astrocytes 3%—Oligodendrocytes 2%—Other 

SVZa 75%—Neuronal progenitors 10%—Neural progenitors 5%—Microglia 10%—Other 

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