Ecotoxicology of Chlorinated Aromatic Hydrocarbons

Becker, T. Phillips and S. Safe, Toxicol. Environ. Chem., 1991, 33, 189. 

Fenical, in Marine Organic Chemistry, ed. E. K. Duursma and R. Dawson, Elsevier, Amsterdam, 1981, ch. 12. 

In the literature, the wildlife ecotoxicology of CACs has not been dealt with to the extent of agrochemicals.18 The purpose of this chapter is to review eco-toxicological aspects of chlorinated aromatic compounds, with emphasis on polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans. Rather than being complete we will try to review recent information on bioaccumulation, biotransformation and effects of CACs. The focus will be on avian and mammalian 

7 PCBs and the Environment, ed. J. S. Waid, CRC Press, Boca Raton, 1986. 

Ballschmiter, C. Rappe and H. R. Buser, in Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products, ed. R. D. Kimbrough and A. A. Jensen, Elsevier, Amsterdam, 1989, ch. 2. 

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De Voogt, R (1996). Ecotoxicology of chlorinated aromatic hydrocarbons. In Chlorinated Organic Micropollutants, No 6 in series Issues in Environmental Science and Technology. R.E. Hester and R.M. Harrison (Eds.) Royal Society of Chemistry 89-112. 

Table 5 Chlorinated polycyclic aromatic hydrocarbons (CIPAH) activity expressed as (a) EROD (ethoxyresorufin-O-deethylase) activity as the relative intensity of ClPAH-mduced cytochrome P450 (CYP) activity in human breast cancer MCF-7 cells [228] (b) environmental fate [Bioaccumulation aquatic] in Pimephales promelas over 96 h [10 L/kg wet] (c) ecotoxicological information [Aquatic Toxicity] LC50 for Pimephales promelas after 96 h [10 mg/L] and (d) carcinogenity in rats, TD50 [10 mol/kg]...

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