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Ecothiopate iodide

CjHjoNOjPS 3147-20-4) see Ecothiopate iodide phosphorus trichloride (C1-,P 7719-12-2) see Isoflurophate phosphoryl chloride... [Pg.2435]

Econosone, 918 Ecostatin, 579 Ecostigmine iodide, 579 Ecothiopate iodide, 579 Ecoval, 393 Ectasule Minus, 584 Ecuagesico, 598, 733 Edecril, 591 Edecrin(e), 591 Edrol, 596... [Pg.1341]

A number of types of parasympathomimetics are used. Muscarinic agonists used include carbachol and pilocarpine (see MUSCARINIC CHOLINOCEPTOR agonists) ANTICHOLINESTERASES include demecarium bromide, dyflos, ecothiopate iodide, pl sostigmine sulphate and pyridostigmine bromide. [Pg.30]

Ecostatin econazolenitrate, ecothiopate ecothiopate iodide, ecothiopate iodide [ban, inn] (echothiopate diethoxyphosphinylthiocholine Ml 217 Camsilon Phospholine Iodide ) is an irreversible (organophosphate group) ANTICHOLINESTERASE. It is a PARASYMPATHOMIMETIC used topically as a miotic in ANTIGLAUCOMA TREATMENT. [Pg.107]

Phospholine Iodide" - ecothiopate iodide. PHOSPHOLIPASE INHIBITORS act at sites on phospholipases, a large group of enzymes with many roles. There are two main groups of enzyme of particular interest in relation to receptor signalling, which makes them important drug targets phospholipase Aj and phospholipase C. These will be discussed in turn. [Pg.220]

The neuromuscular blocking effects of suxamethonium (succinylcholine) are marked increased and prolonged in patients receiving ecothiopate iodide. The dosage of suxamethonium should be reduced appropriately. [Pg.122]

In 1965 a study showed that ecothiopate iodide eye drops could markedly lower pseudocholinesterase levels. It was noted that ... within a few days of commencing therapy, levels are reached at which protracted apnoea could occur, should these patients require general anaesthesia in which muscle relaxation is obtained with succinylcholine . Cases of apnoea due to this interaction were reported the following year, and other cases have been subsequently reported. In one case a woman given suxamethonium (succinylcholine) 200 mg showed apnoea for 5 /2 hours. Other stud-... [Pg.122]

Suxamethonium is metabolised in the body by plasma cholinesterase. Ecothiopate iodide depresses the levels of this enzyme so that the metabolism of the suxamethonium is reduced and its effects are thereby enhanced and prolonged. One study in 71 patients found that two drops of ecothiopate iodide 0.06% three times a week in each eye caused a twofold reduction in plasma cholinesterase (pseudocholinesterase) activity in about one-third of the patients, and a fourfold reduction in 1 in 7 patients. ... [Pg.123]

Pantuck EJ. Ecothiopate iodide eye drops and prolonged response to suxamethonium. BrJ... [Pg.123]


See other pages where Ecothiopate iodide is mentioned: [Pg.729]    [Pg.729]    [Pg.2352]    [Pg.2361]    [Pg.2416]    [Pg.729]    [Pg.729]    [Pg.729]    [Pg.2352]    [Pg.2361]    [Pg.2416]    [Pg.579]    [Pg.1080]    [Pg.1086]    [Pg.1094]    [Pg.3274]    [Pg.98]    [Pg.107]    [Pg.181]    [Pg.349]    [Pg.549]    [Pg.430]    [Pg.122]    [Pg.123]    [Pg.317]   
See also in sourсe #XX -- [ Pg.729 ]

See also in sourсe #XX -- [ Pg.365 ]




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