Binding, drug-receptor

To understand the estimation of average drug-receptor binding energies... 

Prediction of ADME properties should be simple, since the number of descriptors underlying the properties is relatively small, compared to the number associated with effective drug-receptor binding space. In fact, prediction of ADME is difficult The current ADME experimental data reflect a multiplicity of mechanisms, making prediction uncertain. Screening systems for biological activity are typically single mechanisms, where computational models are easier to develop [1],... 

Bennett, J. P. Jr, Yamamura, H. L Neurotransmitter, hormone, or drug receptor binding methods, in Neurotransmitter Receptor Binding, ed. Yamamura, H. L, Enna, S. J., Kuhar, M. J., Raven Press, New York, 1985, pp 61-89. 

Selection of Drug-Receptor Binding Forces in Drug Design... 

CLASSICAL THEORIES OF DRUG-RECEPTOR BINDING INTERACTIONS... 

Thermodynamic Analysis in Drug-Receptor Binding The A3 Adenosine Receptor... 

Gilli P, Ferretti V, Gilli G, Borea PA (1994) Enthalpy-entropy compensation in drug-receptor binding. J Phys Chem 98(5) 1515—1518... 

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