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Drug ontogeny

Key words Children, Pharmacogenomics, Pharmacology, Drug safety, Genetics, Drug ontogeny, Childhood cancer... [Pg.687]

Anand SS, Kim KB, Padilla S et al (2006) Ontogeny of hepatic and plasma metabolism of deltamethrin in vitro role in age-dependent acute neurootoxicity. Drug Metab Dispos 34 389-397... [Pg.105]

Lamartiniere CA, Nicholas JM. 1984. Neonatal chlordecone alteration of the ontogeny of sex-differentiated hepatic drug and xenobiotic metabolizing enzymes. Biochem Pharmacol 33(24) 4092-4095. [Pg.268]

Table 4. Developmental patterns for the ontogeny of important drug metabolizing enzymes in man... Table 4. Developmental patterns for the ontogeny of important drug metabolizing enzymes in man...
The fact that the ontogeny of renal function has been the most well characterized of any organ responsible for drug elimination makes it possible... [Pg.187]

Kearns GL. Ontogeny and pharmacogenetics determinants of age-associated differences in drug clearance during human development. Rotterdam Optima Graflsche Communicatie 2002. [Pg.200]

Cheng X, Maher J, Chen C, et al. Tissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps). Drug Metab Dispos 2005 33 1062-1073. [Pg.184]

Alnouti Y, Petrick JS, Klaassen CD. Tissue distribution and ontogeny of organic cation transporters in mice. Drug Metab Dispos 2006 34 477 -82. [Pg.187]

Maharajan P, Maharajan V, Ravagnan G, Paino G (2001) The weaver mutant mouse a model to study the ontogeny of dopamine transmission systems and their role in drug addiction. Prog Neurobiol 64 269-276. [Pg.291]

Choudhary, D., Jansson, I., Sarfarazi, M., and Schenkman, J. B. Xenobiotic-metabolizing cytochromes P450 in ontogeny Evolving prespective. Drug Metab. Rev. 36, 549-568, 2004. [Pg.271]

Hines, R. N., and McCarver, D. G. The ontogeny of human drug-metabolizing enzymes Phase I oxidative enzymes. J. Pharmacol. Exp. Ther. 300, 355-360, 2002. [Pg.271]

McCarver DG, Hines RN (2002) The ontogeny of human drug-metabolizing enzymes phase 2 conjugation enzymes and regulatory mechanisms. J Pharmacol Exp Ther 300 361-366. [Pg.128]

Because clinical investigation of new agents is not uniformly performed in newbornS/ infantS/ and children/ we have a poor understanding of the effect of ontogeny on the pharmacokinetics and pharmacodynamics of most drugs. However/ we can often anticipate age-related differences in pharmacokinetics and... [Pg.362]

Blake MJ, Castro F, Feeder JS, Kearns GF. Ontogeny of drug metabolizing enzymes in the neonate. Semin Fetal Neonatal Med 2005 10 123-38. [Pg.372]

Reed, M.D. The ontogeny of drug disposition Focus on drug absorption, distribution, and excretion. Drug Inform. J. 1996, 30, 1129-1134. [Pg.2648]

John EG Guignard JP. Development of renal excretion of drugs during ontogeny. In Neonatal and fetal medicine. Polin RA FowWW Eds. Saunders WB, Philadelphia, pp 188-193,1997. [Pg.64]

See other pages where Drug ontogeny is mentioned: [Pg.1267]    [Pg.192]    [Pg.240]    [Pg.181]    [Pg.182]    [Pg.185]    [Pg.186]    [Pg.187]    [Pg.188]    [Pg.191]    [Pg.192]    [Pg.89]    [Pg.60]    [Pg.64]    [Pg.50]    [Pg.51]    [Pg.52]    [Pg.65]    [Pg.132]    [Pg.125]    [Pg.117]    [Pg.125]    [Pg.510]    [Pg.441]    [Pg.36]    [Pg.359]    [Pg.372]    [Pg.136]   
See also in sourсe #XX -- [ Pg.673 , Pg.688 , Pg.689 ]



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