Drug life cycle stages

Table 12.1 Drug life cycle stages and regulatory requirements...

Drug life cycle stage Regulatory requirements/Guidelines... 

SEP increases since the implementation of the SEP Drug life cycle stages and regulatory requirements Donor support of local industry through contracting for local health supplies Zimbabwe Finance capabilities at the firm and financial institution levels... 

To assist the reader with the question of which dissolution test to apply when the first part of this chapter is divided into two primary sections—one dealing with drugs that have few or no solubility problems, in which case developing dissolution tests at all stages of the product life cycle... 

Plasmodia. Malaria parasites. These have a complex life cycle both in the mosquito and in the vertebrate host. Parasites in different stages of development, e.g. in the liver, in the red blood cell and the gametocytes which infect mosquitos, respond differently to drugs. 

Figure 8.1 The general stages and their relationships in the life cycle of a drug after administration...

The effectiveness of a drug treatment is related to the particular species of infecting plasmodium and the stage of its life cycle. A summary of the life cycle of the parasite and the sites of therapeutic interventions are presented in Figure 35.4. 

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