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Drug discovery fast chromatography

Hsieh Y. et al., 2001. Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 15 2481. [Pg.295]

M. M. et al. Brain and plasma exposure profiling in early drug discovery using cassette administration and fast liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal 2004, 34, 359-368. [Pg.424]

Tiller, P. R. Romanyshyn, L. A. Implications of matrix effects in ultrafast gradient or fast isocratic liquid chromatography with mass spectrometry in drug discovery. Rapid Commun Mass Spectrom 2002, 16, 92-98. [Pg.425]

Hsieh, Y., Chintala, M., Mei, H., Agans, J., Brisson, J. M., Ng, K., and Korfmacher, W. A. (2001). Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma [by] using fast-gradient liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 15 2481-2487. [Pg.118]

Chu I, Liu F, Soares A, Kumari P, Nomeir AA. Generic fast gradient liquid chromatography/ tandem mass spectrometry techniques for the assessment of the in vitro permeability across the blood-brain barrier in drug discovery Rapid Common Mass Spectrom 2002 16(15) 1501-1505. [Pg.161]

Wainhaus, S. et al., Ultra fast liquid chromatography-MS/MS for pharmacokinetic and metabolic profiling within drug discovery, Am. Drug Discov., 2(1), 6, 2007. [Pg.31]


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Drug discovery chromatography

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