Drug delivery local modes

De Scheerder I, Xianshun Liu, Chevalier B, LeClerc G, Colias A. Batimastat mode of action, preclinical and clinical studies. In Camenzind E, De Scheerder I, eds. Local Drug Delivery for Coronary Artery Disease. London and New York Taylor Francis, 2005 483-498. 

The flow moderator is then inserted through the portal, to restrict the diffusional mode of solute exit, assuring that the osmotic process will control the delivery rate. If the transparent overcap is removed from the flow moderator, a catheter (PE 50 or 60 size) can be attached for localized administration of drugs to areas remote from the site of implantation or to target organs. 

---