Droplet Based Lab-on-Chip Devices

Droplet-Based Lab-on-Chip Devices, Fig. 1 Layout of electrowetting chip with droplet translation onto actuated electrodes... 

Droplet-Based Lab-on-Chip Devices Droplet Dispensing... 

Droplet based Lab-on-Chip devices represent a class of microfluidic systems that have been developed to miniaturize chemical, biochemical or cellular analysis. These devices utilize various droplet dispensing and manipulation mechanisms to isolate and control liquid-phase droplets of sanities and/or reagents surrounded by a gas or an immiscible liquid. The droplets may be completely surrounded by the medium or may be placed onto a solid surface whose material properties are chosen to provide droplet confinement, chemical functionalization, or control of droplet motion. The devices also have some type of assay read-out method with associated hardware, software and data display. 

Droplet Based Lab-on-ChIp Devices, Figure 2 Typical electrowetting droplet Lab-on-Chip design using home-run wiring with switching electronics off-chip. Chips of this type have been used to initiate DNA amplification reactions shown below... 

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