Dosage, radiological

Senna is widely used in fairly low doses without serious problems it has also been used in a very high dosage form to clear the colon before radiological examination. In this form it is generally well tolerated, but it should not be used if there is any predisposition to colonic rupture. 

Despite the fact that acetylsalicylic acid has been used for many years, it is only recently that controlled trials have demonstrated its efficacy in the symptomatic treatment of rheumatoid arthritis - . The results of a 3 year multi-centre trial comparing cortisone acetate and acetylsalicylic acid, given in the lowest dosage needed to keep each patient symptom-free, indicate that the efficacy of both drugs is similar in almost all respects . The condition of the patients after 3 years was better than at the start of the trial, but radiological deterioration occurred in both groups. 

In a phase II open label study of arjuna in patients with severe refractory heart failure, patients stabilized on digitalis and/or diuretic and vasodilator drugs were orally administered 500 mg of a hydroalcoholic extract of arjuna bark every 8 hours for 4 months. Biochemical, electrocardiographic, radiological, and echocardiographic parameters were monitored. No adverse events were reported, and in all cases patients were able to reduce the diuretic dosage to the minimum necessary to keep symptom free (Bharani et al. 1995). 

Billard, R, Miribel, J., Madeleine, G., Pradel, J. (1964). Methodes de mesure du radon et de dosage dans les mines d uranium. In Radiological Health and Safety in Mining and Milling at Nuclear Materials, vol. I. IAEA, Vienna, STI/PUB/78,pp. 411-423. 

In radiological imaging such as PET or CT scans, dosages of pharmaceuticals are based on body mass. If a person weighs 165 lb, what is that body mass in kilograms ... 

Eq. (5-2) may be utilized in estimating thyroidal uptake. If a daily intake of 0.15 mg is assumed, then thyroidal uptakes at 24 hours would remain at about 27 percent for dosages of less than 1 nCi (5.9 ng iodine). However, at higher dosages of there would be a considerable reduction in thyroidal uptake, to about 10 percent from 0.1 ltd I (0.59 mg -I- 0,15 mg), to about 3 percent from 1 tCi (5.9 mg -I- 0.15 mg). Since the radiologic dose to the thyroid is determined by the concentration in the gland, a similar decrease in dose per unit intake would be predicted. 

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