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Dopaminergic ligand-receptor system

Neuroleptic drugs are used in the treatment of psychosis, such as schizophrenia they are generally antagonist ligands of dopamine at the central nervous system level. " Indications and therapeutic effects of the various families of neuroleptics result from two factors. The first one is the specifity of the ligand toward the different types of dopaminergic receptors, which are unequally distributed in the... [Pg.300]

The focus of most human studies to date has been on the dopamine D2 receptor and to some extent DATs in regard to neuropsychiatric disorders. It is important to emphasize that improved understanding of the in vivo dopaminergic system in disease and normal subjects is dependent on the development of specific ligands to characterize other dopaminergic markers, such as the D3, D4 and D5 receptors, that have a much more... [Pg.558]


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Dopaminergic

Dopaminergic receptors

Dopaminergics

Receptor ligands

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