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Dopamine synaptosome release

Dennis J. McKenna, X.-M. Guan, and A. T. Shulgin. "3,4-methyl-enedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine." Pharmacology, Biochemistry, and Behavior 38 (1991) 505-12. [Pg.176]

Mcl nna, D.J. etal. i99r. 3,4-Methylene-dioxyamphetamine (mda) analogues exhibit differential effects on synaptosomal release of H-dopamine and H-5-hydrox-ytryptamine Pharmacology Biochemistry and Behavior 505-512. [Pg.273]

It could not be anticipated that the extension of the alpha-methyl of MDMA to an alpha-ethyl would also attenuate the effects of the compound on dopaminergic pathways in the brain. In contrast to MDMA, MBDB has no significant effect either on inhibition of uptake of dopamine into striatal synaptosomes (Steele et al. 1987) or on release of dopamine from caudate... [Pg.7]

We are routinely screening compounds for ability to displace 1-125 DOI from frontal cortex homogenates. As far as the CNS stimulant effects, differentiating from psychostimulants, the present model we are using is substitution in amphetamine-trained rats, in drug discrimination. We have used synaptosomes and looked at their effect on dopamine release and reuptake. But basically they are correlative models. [Pg.19]

Accumulation of amphetamine and / -chloroamphetamine into synaptosomes of rat brain. J Pharm Pharmacol 24 171-173, 1972. Yamamoto. B.K., and Spanos, L.J. The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat. Eur J Pharmacol 148 195, 203, 1988. [Pg.357]

Masuoka, D.T., Alcaraz, A.R, and Schott, H.F., [3H]Dopamine release by d-amphetamine from striatal synaptosomes of reserpinized rats, Biochem. Pharmacol., 31, 1969, 1982. [Pg.13]

Bowyer, J.F., Spuler, K.P., and Weiner, N., Effects of phencyclidine, amphetamine and related compounds on dopamine release from and uptake into striatal synaptosomes, J. Pharmacol. Exp. Ther., 229, 671, 1984. [Pg.14]

Rapier, C., Lunt, G.G., and Wonnacott, S., Stereoselective nicotine-induced release of dopamine from striatal synaptosomes concentration dependence and repetitive stimulation, J. Neurochem., 50, 1123, 1988. [Pg.19]

Hetey, L., Schwitzlowsky, R., and Oelssner, W., Influence of psychotomimetics and lisuride on synaptosomal dopamine release in the nucleus accumbens of rats, Eur. J. Pharmacol., 93, 213, 1983. [Pg.21]

Hetey, L. and Quirling, K., Synaptosomal uptake and release of dopamine and 5-hydroxytryptamine in the nucleus accumbens in vitro following in vivo administration of lysergic acid diethlamide in rats, Acta Biol. Med. Ger., 39, 889, 1980. [Pg.21]

Kulak, J.M., Nguyen, T.A., Olivera, B.M., McIntosh, J.M. alpha-Conotoxin MB blocks nicotine-stimulated dopamine release in rat striatal synaptosomes. J. Neurosci. 17 5263, 1997. [Pg.32]

Grady, S.R., Marks, M.J., Collins, A.C. Desensitization of nicotine-stimulated [3H]dopamine release from mouse striatal synaptosomes. J. Neurochem. 62 1390, 1994. [Pg.32]

Poddar MK, Dewey WL. 1983. Kepone induced changes in the synaptosomal uptake and release of dopamine in corpus striatum and norepinephrine in hypothalamus. IRCS Medical Science Library Compendium 11 (7) 632-633. [Pg.279]

Clarke PB, Reuben M. (1996). Release of [3FI]-noradrenaline from rat hippocampal synaptosomes by nicotine mediation by different nicotinic receptor subtypes from striatal [3FI]-dopamine release. BrJ Pharmacol. 117(4) 595-606. [Pg.448]

Recently, we (Salminen et al. 2004) evaluated the effects of deleting the a2, oc4, a5, al, (32, p3, and p4 genes on both the a-CtxMIl-sensitive and resistant components of ACh-stimulated [ H]-dopamine release from striatal synaptosomes. Deletion of the oc4 and p2 subunit genes resulted in the total elimination and a5 gene deletion produced a significant decrease in the aCtxMll-resistant... [Pg.103]

Kulak JM, Nguyen TA, Olivera BM, McIntosh JM (1997) Alpha-conotoxin Mil blocks nicotine-stimulated dopamine release in rat striatal synaptosomes. J Neurosci 17 5263-5270 Kuryatov A, Gerzanich V, Nelson M, Olale F, Lindstrom J (1997) Mutation causing autosomal dominant nocturnal frontal lobe epilepsy alters Ca + permeabihty, conductance, and gating of human a4 32 nicotinic acetylcholine receptors, J Neurosci 17 9035-9047 Kuryatov A, Olale FA, Choi C, Lindstrom J (2000) Acetylchohne receptor extracellular domain determines sensitivity to nicotine-induced inactivation, Eur J Pharmacol 393 11-21 Langley JN (1880) On the antagonism of poisons. J Physiol 3 11-21... [Pg.108]

Sharpies CG, Kaiser S, SoUakov L, Marks MJ, Collins AC, Washburn M, Wright E, Spencer JA, Gallagher T, Whiteaker P, Wonnacott S (2000) UB-165 a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2 subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci 20 2783-2791... [Pg.111]

Soliakov L, Gallagher T, Wonnacott S (1995) Anatoxin-a-evoked [ H]dopamine release from rat striatal synaptosomes. Neuropharmacology 34 1535-1541 Soliakov L, Wonnacott S (1996) Voltage-sensitive Ca channels involved in nicotinic receptor-mediated [ H]dopamine release from rat striatal synaptosomes. J Neurochem 67 163-170 Sorge R, Clarke PB (2007) Slow/low intravenous infusions of nicotine in rats a better model of smoking Soc Neurosci Abst 37 273.17... [Pg.205]

Rowell PP, Winkler DL Nicotinic stimulation of [ HJacetylchoUne release from mouse cerebral cortical synaptosomes. J Neurochem 43 1593-1598, 1984 Roy A, Karoum F, Pollack S Marked reduction in indexes of dopamine metabolism among patients with depression who attempt suicide. Arch Gen Psychiatry 49 447-450, 1992... [Pg.736]

L. Soliakov, T. Gallagher and S. Wonnacott, Anatoxin-a-evoked 3H dopamine release from rat striatal synaptosomes, Neuropharmacology, 34... [Pg.348]

Sarhan H, Cloez-Tayarani I, Massot O, Fillion MP, Fillion G (1999) 5-HTib receptors modulate release of [3H] dopamine from rat striatal synaptosomes. Naunyn Schmiedeberg s Arch Pharmacol 359 40-7... [Pg.335]

Michaelis ML, Michaelis EK, Myers SL (1979) Adenosine modulation of synaptosomal dopamine release. Life Sd 24 2083-92... [Pg.368]

See other pages where Dopamine synaptosome release is mentioned: [Pg.94]    [Pg.240]    [Pg.100]    [Pg.345]    [Pg.339]    [Pg.27]    [Pg.56]    [Pg.62]    [Pg.101]    [Pg.103]    [Pg.104]    [Pg.107]    [Pg.107]    [Pg.163]    [Pg.183]    [Pg.183]    [Pg.184]    [Pg.115]    [Pg.184]    [Pg.189]    [Pg.1776]    [Pg.333]    [Pg.346]   
See also in sourсe #XX -- [ Pg.94 ]



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