Methadone Disulfiram

DRD2 Dopamine receptor D2 rs6277, rsl799978, rs6275 Cocaine, alcohol, opioids Acamprosate, bromocriptine, disulfiram, methadone... 

Ling W, Weiss DG, Charuvastra VC, et al Use of disulfiram for alcoholics in methadone maintenance programs. Arch Gen Psychiarry 40 851—854, 1983 Ling W, Charuvastra C, Collins JF, er al Buprenorphine maintenance treatment of opiate dependence a multi-center, randomized clinical trial. Addiction 93 475-486, 1998... 

Studies have shown that CM can be used to directly reinforce adherence to medication treatments as well (Petty 2000). Liebson et al (1978) found that methadone-maintained alcohol-dependent patients reduced alcohol use when methadone treatment was contingent on disulfiram consumption. To date, one of the most common applications of CM techniques to pharmacotherapy has been the provision of vouchers or cash contingent upon naltrexone consumption in recently detoxified opioid-dependent patients (Carroll et al. 2001, 2002 Preston et al. 1999). These studies have generally reported significant increases in retention and reductions in opioid use among patients receiving the CM treatment, relative to other therapies. 

Drugs that might affect amprenavir include abacavir, aldesleukin, antacids, anticonvulsants, azole antifungals, clarithromycin, cyclosporine, dexamethasone, buffered didanosine, disulfiram, ethanol, indinavir, methadone, metronidazole, nelfinavir, nonnucleoside reverse transcriptase inhibitors, oral contraceptives, rifamycins, ritonavir, saquinavir, St. John s wort, tacrolimus, and zidovudine. 

Brewer C (1996). On the specific effectiveness, and under-valuing, of pharmacological treatments for addiction a comparison of methadone, naltrexone and disulfiram with psychosocial interventions. Addiction Research, 3, 297-313... 

ANKK1 Ankyrin repeat and kinase domain-containing 1 rsl800497 (TaqIA) Cocaine, alcohol, opioids Disulfiram, naltrexone, methadone... 

Disulfiram (Table 1) was tested in a cohort of cocaine and opioid codependent individuals as a pharmacotherapy for cocaine addiction in a placebo controlled clinical trial [52], Patients were stabilized on methadone and the treatment group received 250 mg of disulfiram daily. Disulfiram pharmacotherapy decreased cocaine use as measured by urine cocaine metabolites, with no concomitant... 

Petrakis IF, Carroll KM, Nich C, Gordon FT, McCance-Katz EF, Frankforter T, Rounsaville BJ (2000) Disulfiram treatment for cocaine dependence in methadone-maintained opioid addicts. Addiction 95 219-228... 

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