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Distribution studies mass spectrometric imaging

Distribution Studies of Drugs and Metabolites in Tissue by Mass Spectrometric Imaging... [Pg.449]

In 2006, Lobinski et al.1 reported on the imaging and speciation analysis of trace elements to study the element distribution, oxidation state, metal site and metal structure in biological environments using mass spectrometric techniques (LA-ICP-MS, SIMS, MALDI-MS) and non-mass-spectrometric techniques such as micro-PIXE (proton induced X-ray emission), XANES (X-ray absorption near edge structure) and EXAFS (extended X-ray absorption fine structure) -the latter two techniques are very sensitive due the use of a more intense synchrotron beam.1... [Pg.336]

Imaging mass spectrometric techniques using LA-ICP-MS was developed for imaging the distribution of metals and non-metals in thin sections of biological tissnes. The qnantitative imaging analysis of essential and toxic elements in biological tissnes allows studies to be performed of element distribntion, transport processes, bioavailability, and possible contamination. [Pg.78]

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Distribution studies

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Mass spectrometr

Mass spectrometric

Mass spectrometric imaging

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