Dissolution HPLC chromatogram

Figure 6.12 shows the dissolution HPLC chromatogram of the product in 3% sodium dodecylsulfate (SDS) at pH 6.8. SDS was required in the media... 

FIGURE I Typical fast HPLC chromatograms for a set of three dissolution samples at three time points. 

Figure 11.3 HPLC chromatograms of dissolution sample solution for 10 xg Compound X capsules using large volume injection.

Alkyl polyglycoside characterization by HPLC is routinely performed using an isocratic reversed-phase system. In most cases, no particular sample preparation is necessary after dissolution in the eluent, the sample solution is filtered and directly injected into the system. A typical chromatogram and the chromatographic conditions are shown in Figure 10. 

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