Disorientation molecular

The analysis of the molecular basis for unexpected responses of ultrarapid CYP2D6 metabolizers to codeine follows a similar line of reasoning. The ultrarapid metabolizers have enhanced capacity to metabolize codeine and hence may exhibit exaggerated responses, such as abdominal cramping, fuzzy vision and disorientation.(113) Because ultrarapid metabolizers occur more frequently among Hispanic, African and Saudi Arabian than Asian populations,(106) the former groups would be more likely to experience exaggerated responses to codeine. 

Obtaining an efficient NLO switching material is not easy, because reversibility of molecular change provided by a reversible chemical reaction does not always imply the reversibility of macroscopic physical properties. Further studies should focus on the photochromic molecule itself as well as on the type of material used. On a molecular scale, a photochrome exhibiting large diflercnccs between the two properties of the two forms and efficient conversion should be examined. Concerning the material, there is a subtle trade-off between the rigidity so that disorientation can be avoided, and flexibility so that the photochromic reaction can efficiently take place. 

The receptor proteins on the membrane may undergo molecular disorientation during the interaction of acetylcholine with... 

These phenomena can be interpreted in terms of molecular orientation by the velocity gradient in the flowing liquid, opposed by the rotary Brownian movement which produces disorientation and a tendency toward a purely random distribution. The intensity of this Brownian movement is charaterized by the rotary diffusion constants, 0, discussed in the preceding section. The fundamental treatment of this problem, for very thin rod-shaped particles, was given by Boeder (5) the treatment has been generalized, and extended to rigid ellipsoids of revolution of any axial ratio, by Peterlin and STUARTi 56), [98), (99) and by Snell-MAN and Bj5knstAhl (J9J). The main features of their treatment are as follows 1 ... 

The problem would be solved if only

decay function is probably quite complex, since the rate of disorientation must be influenced by interactions between dipoles and by the molecular field. Nevertheless it has often been assumed that this speed of decay is proportional to the orientation polarization itself, so that we have the well-known exponential law ... 

Secondary flow, combined with molecular diffusion promotes the radial transport in a powerful way. Its intensity increases with geometrical disorientation of the flow path. Thus, coiling of the tubes induces a gentle... 

When the composition and molecular asymmetry are kept constant, Eq. (3.40) goes through a minimum, and then a maximum, as the disorientation parameter y increases. Since there are no external restraints on the disorientation index, y... 

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