Dismissal other reasons

A. H. Emery Co. vs. Marcan (9) involves both a patent and trade secret situation. The patent was invalid. The former employer prevailed on the trade secret aspects. A confidential relationship survived a termination of employment even though one of the former employees was dismissed for other reasons before the group of former employees started their activities. 

The idea of an atom has been so constantly associated with incredible assumptions of infinite strength, absolute rigidity, mystical actions at a distance and indivisibility, that chemists and many other reasonable naturalists of modem times, losing all patience with it, have dismissed it to the realms of metaphysics, and made it smaller than "anything we can conceive". 

If we are required to prove significance in two trials, as is usually believed to be necessary in phase III for a successful NDA application, then from the practical point of view it may be the power of the combined requirement which is important, rather than that for individual trials. On the assumption that the trials are competent and that the background planning has been carried out appropriately and that trial by treatment interactions may be dismissed, then the power to detect the clinically relevant difference in both of two trials, each with power 80%, is 64% since 0.8 x 0.8 = 0.64. This means that 1 — 0.64 = 0.36, or more than one-third, of such drug development programmes would fail in phase III for failure of one or both clinical trials on this basis. (This does not mean that one-third of drug developments will fall in phase III, since many drugs which survive that far may, indeed, have an effect which is superior to the clinically relevant difference. On the other hand, there may be other reasons for failure.) If it is desired to have 80% power overall, then it is necessary to run each trial with 90% power since 0.9 x 0.9 = 0.80. 

The N-to-C assembly of the peptide chain is unfavorable for the chemical synthesis of peptides on solid supports. This strategy can be dismissed already for the single reason that repeated activation of the carboxyl ends on the growing peptide chain would lead to a much higher percentage of racemization. Several other more practical disadvantages also tend to disfavor this approach, and acid activation on the polymer support is usually only used in one-step fragment condensations (p. 241). 

Thus, in response to Pfizer s asserted superior and unexpected results, the court, at various places, reasoned a particular result (e.g., solubility, chemical stability, ease of manufacturability) was not superior, not unexpected, or both not superior and not unexpected. This analysis, combined with the court s dismissal of Pfizer s other arguments for nonobviousness, resulted in invalidation of Claims 1-3 of the 303 patent. 

Having obtained what I believe to be a sound value of kp for styrene in nitrobenzene, it is appropriate to attempt a comparison with values obtained in other solvents and in bulk. As for the latter, the radiation results still show a scatter over 2 orders of magnitude (2 x 106 to 4 x 10s 1 mol 1 s 1) without there being any evident reasons for narrowing the range by dismissing either of the extremes however, the more recent results seem to be grouped near the lower value (3). 

Although menopause is an important initiator for sleeping problems, sleep disturbances may just coincide with the menopausal period. Thus other explanatory factors behind should not be dismissed but evaluated with similar intensity at different periods around menopause. The most important reasons embrace depressive mood, stress, behavioral factors, as well as restless leg syndrome (RLS) and periodic limb movement syndrome (PLMS). 

I agree that ideally farmers would be able to control weeds in other ways and avoid spraying anything at all. Besides, it is costly to buy herbicides, and is therefore not useful to farmers in less developed nations who cannot afford the price. But I do know that for all farmers weeds are a big problem and cannot be dismissed lightly. For instance, Raoul tells me that weeds are the main reason why organic rice yields are often lower than conventional yields. 

The reason other writers have dismissed it as having no practical application is probably because they don t think along the lines of improvised weaponry- But I do. t made about a teaspoonful and spread it about an eighth of an inch, thick on my work table and let it dry. Then 1 barely touched it with a feather. Instead of the snap-cracKle-pop effect described in the book, it was a real explosion. The table was pitted and my ears rang. After having made far more than required to demonstrate this arra iingly unstable substance, t was struck by its heretofore unmen-tionod potential as a weapon. 

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