Disconnection method

While the divergent-growth approach allowed an entry into the field of dendritic macromolecules and its use continues to produce novel and fascinating structures, the need existed to develop a complementary approach to synthesize dendritic macromolecules. To develop an alternate strategy, we decided to apply the disconnection method in organic... 

When introducing the disconnection method and synthesis, making the correct disconnection often seems more important than the chemical reactions and concepts required to form the disconnected bond. In reality, the disconnection is dictated by the ability to form the bond in the context of stereochemistry and selectivity, not the other way around. The synthesis of organic molecules dates to the nineteenth century, but the work of... 

This chapter has reviewed the most fundamental concepts of stereochemistry and conformational analysis, with some applications to more complex problems. For students who have had a good undergraduate organic chemistry course, it is intended as a review, since these concepts are integral to the understanding of organic reactions. The concept of disconnection and retrosynthetic analysis is a prelude to a discussion of synthetic strategies in Chapter 10. The disconnection method and pertinent transforms will, however, be presented in virtually every chapter as new reactions are introduced. 

A hand-operated power disconnect device shall disconnect the whole equipment from main input supply power. There are several possibilities. A user-accessible disconnect switch located on the front of the product is preferred but not the only option. Some of the power disconnect methods are ... 

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