Disclaimers

This chapter was written by Dr. Stephen C. DeVito, a scientist with the US Environmental Protection Agency, in his private capacity. The contents of this chapter do not necessarily reflect the views, rules, positions, policies, or practices of the US Environmental Protection Agency, nor does mention of any chemical substance constitute an official Agency endorsement or recommendation for use. 

Hamilton, A. (1928) Protection against industrial poisoning, (ed. J.S. Stieglitz) Chemistry in Medicine, 1st edn., 

Williams R.T. (1947) Detoxication Mechanisms the Metabolism of Drugs and Allied Organic Compounds, John Wiley Sons, Inc., New York. 

Burger, A. (1951) Medicinal Chemistry Chemistry, Biochemistry, Therapeutic and Pharmacological Action of Natural and Synthetic Drugs, Vol. I, Interscience, 

The primary set of references for this manuscript was retrieved from the Science Citation Index, accessed via BIDS (Bath Information and Data Services, University of Bath, UK). The completeness of the first automated selection of papers depends on the accuracy of the information present in the Science Citation Index, the determination of the non-trivial publication time window (June 1998 to June 1999) set by our publisher, and the accuracy of the reference to Bader s 1990 monograph in the original paper. All papers appearing in readily obtainable journals were screened in full and included if they were of sufficient interest from the point of view of AIM. When in doubt it was decided to exclude a possible paper in favour of other papers with higher AIM content. This choice was determined by space restrictions and the readability of the report. We apologise to authors for the possibly erroneous omission of their work, but believe that we have provided a rather complete and unbiased reflection of the research activity in the AIM area. 

Gillespie and P. L. A. Popelier, The Chemical Bond and Molecular Geometry from Lewis to Electron Densities , Oxford University Press, New York, 2001. 

Atoms in Molecules. A Quantum Theory , Oxford University Press, 1990. 

Angyan, G. Jansen, M. Loos, C. Haettig and B. A. Hess, Chem. Phys. Lett., 1994, 219, 267. 

Popelier, in Molecular Similarity in Drug Design , ed. P. M. Dean, Chapman Hall, London, 1995. 

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Was the Invention Abandoned The invention cannot have been abandoned. An invention may be abandoned either expressly or impHedly. For example, abandonment may occur when an inventor expressly disclaims the invention by dedicating it to the pubHc. Abandonment may also occur if a patent appHcant fails to complete the examination of a patent appHcation pending within the U.S. PTO during the time periods set for completion. The pubHcation of an article disclosing the invention may be an abandonment where the inventor does not file an appHcation for a patent within one year. 

It is sincerely hoped that the information presented in this document will lead to an even more impressive record for the entire industry however, the American Institute of Chemical Engineers, its consultants, CCPS Subcommittee members, their employers, their employers officers and directors, and Arthur D. Little, Inc., disclaim making or giving any warranties or representations, express or implied, including with respect to fitness, intended purpose, use or merchantability and/or correctness or accuracy of the content of the information presented in this document. As between (1) American Institute of Chemical Engineers, its consultants, CCPS Subcommittee members, their employers, their employers officers and directors, and Arthur D. Little, Inc., and (2) the user of this document, the user accepts any legal liability or responsibility whatsoever for the consequence of its use or misuse. 

The information in this book is collected from published and unpublished literature. Responsibility for the accuracy of this material is disclaimed, however, responsibility is accepted for the selection, organization, and presentation. The vastness of the information necessitates selectivity in the attempt to make a comprehensive and cohesive presentation. The material is selected to illustrate a procedure or principle not advocacy. Every effort toward objectivity was made to balance human health and safety, environment, economic welfare, and civilization. 

Source Adapted from Ref. 1. Information in Table 2 is reproduced from technical literature by permission of ICI Surfactants subject to the following disclaimer The information and recommendations in this publication arc believed to be accurate and arc given in good faith, but the Customer should sati.sfy itself of the suitability of the contents for a particular purpose. ICI gives no warranty as to the fitness of the Product information and recommendations for any particular purpose and any implied warranty or condition (statutory or otherwise) is excluded except that such exclusion is prevented by law. Freedom under Patent, Copyright and Designs cannot be assumed."... 

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