L-methyl-4,5-diphenyl

Imidazole, 2-methyl-4,5-diphenyl-l-vinyl-synthesis, S, 488 Imidazole, 1-methylnitro-reactions... 

N N ligand = Ph-bimp = 2.6-bis[bis 2-(l-methyl-4,5-diphenyl -imidazolyl)-methyl aminomethyl]-4-methylphenolate... 

Much work has been done on configuration and conformation, e.g. of 2-methoxy-2-oxo-4,5-diphenyl-l,3,2-dioxaphospholanes with 170 and lsO labelled reagents (81CC245). A large number of 2-dimethylamino-l,3,2-dioxaphospholanes or 3-methoxy-2-methyl-l,3,2,-oxazaphospholanes are mentioned in a recent publication, in which spiro compounds of the general structure (108) were prepared by addition to diethyl azodicarboxylate (equation (69)) (80PS(8)147>. 

Diphenyl-l,2,3-selenadiazole 138 and 3,5-diphenyl-l,2,4-selenadiazole 79 were alkylated with trimethylsilyl-methyl trifluoromethanesulfonate to give the salts 139 and 140 (Scheme 8) <2001J(P1)394>. Quaternizations occurred at N-3 and N-2, respectively. The structures and quaternization sites were confirmed by H, 13C, and 1SN NMR spectra and the subsequent reactions. The salts 139 and 140 were desilylated to generate transient selena-diazoliumylmethanide (ylide) intermediates. The transformation is described in Section 6.12.8. 

The mesoionic 4,5-diphenyl-l,3,4-thiadiazolium-2-thiolate (114) reacts with methyl azodicarboxylate to yield the azothiadiazole (115) and not the tetrazine betaine (116) as previously claimed. Compound (115) can also be prepared from 2-amino-5-phenyl-l,3,4-thiadiazole and nitrosobenzene (71CC837). 

However, reaction of diazomethane with methyl dithiobenzoate leads to a mixture of cis and Irons diastereomeric 4,5-bis(methylthio>4,5-diphenyl-l,3-dithiolanes (ci.v-5 and trans-5) in a ratio of 66 3451. 

Diphenyl-2-chloroethanone with sodium methyl trithiocarbonate in alcohol, then with perchloric acid, gives 2-methylthio-4,5-diphenyl-l,3-dithiolium perchlorate in 35% yield (Eq. 32). ... 

Dimethyl-3-oxido-l,4,5-triphenyl- - 3041 4,5-Diphenyl-6-methyl-3-thiolato- - 3060 6-Methyl-3-thiolato-3,4,5-triphenyl- - 3060 3-Oxido-1,4,5-triphenyl- 3041 3-Thiolato-l,4,5-triphenyl- - 3060... 

Many ring-fused imidazole derivatives have been synthesized by various methods. Domino Michael addition retro-ene reaction of 2-alkoxyiminoimidazolidines and acetylene carboxylates provided a synthesis of 2,3-dihydroimidazo[l,2-a]pyrimidin-5-(l//)-ones <05T5303>. A single step synthesis of 3,5-dialkyl-9-nitroimidazo[l,2-c]quinazolin-2(3//)-ones from simple carbonyl compounds, primary amines or amino acid methyl esters and 2-azido-5-nitrobenzonitrile has been published <05TL5778>. Diels-Alder reaction of azadienes and benzimidazole-4,7-diones afforded imidazo[4,5-g ]quinoline-4,9-dione derivatives <05EJ01903>. Reaction between isocyanides and dialkyl acetylenedicarboxylates in the presence of 4,5-diphenyl-l,3-dihydro-2//-imidazol-2-one provided a one-pot synthesis of 5//-imidazo[2,l-ft][l,3]oxazine derivatives <05T2645>. Microwave irradiation was employed in the synthesis of 1-ary 1-3-acetyl-1,4,5,6-... 

Disubstituted cyclopropenes undergo addition to tetraarylcyclopentadienones to produce mixtures of exo- and emfo-adducts in which the endo-isomer predominates (Table 12).187188 The predominance of enr/o-product has been explained in terms of secondary orbital interactions, involving the methylene group of the cyclopropene.147 3-Methyl-3-vi-nylcyclopropene reacted with 2,3,4,5-tetraphenylcyclopenta-2,4-dien-l-one at the cyclopropene double bond and a [4+2] cycloadduct of unspecified stereochemistry was isolated (41% mp 231-234 °C) together with decarbonylated products reaction of 2-oxo-4,5-diphenyl-l,3-bis(methoxycarbonyl)cyclopentadiene with 3-methyl-3-vinylcyclopropene was more complicated and apparently attack occurred at both 71-bonds.1... 

Bis-[l,3-Benzothiazol-2-ylthio]-organo- 997 Bis-[4-tert.-butyl-1,3-thiazol-2-yl]- 71 Bis-[l,3-dimethyl-lH-pyrazol-5-yl]- 557 Bis-[4,5-diphenyl-l,3-thiazol-2-yl]- 71 Bis-[4-methyl-l,3-thiazol-2-yl]- 71 Bis-[5-nitro-l,3-thiazol-2-yl]- 244 Bis-[l,3-thiazol-2-yl]- 70, 71 Ethyl- 337... 

Trimcthyl- 408 4H-Pyrazol 409 i 3 4- (4-Brom-phenyl)-l-(4,5-diphenyl-l,3-thiazol- 2-yl)-2-oxo-2,3-dihydro- 68 5- Ethoxycarbonyl-4-mercapto-l-methyl- 339 5-Mercapto- 339 1-Methyl- 710 l-Methyl-2-(2-phenyl-4-trifluormethyl-1,3-thiazol-5-yl)- 293... 

Oxidation of heterocyclic amino derivatives yields various reaction products depending on the structure of the amine. 4-Benzylamino-3-methyl-4//-1,2,4-triazole is oxidized with DCT in chloroform to give the azomethine derivative 110 (69ZC325). l-Amino-4,5-diphenyl-l,2,3-triazole under the action of CBT forms diphenylacetylene 2-aminobenzotriazole yields cis, cw-l,4-dicyanobuta-l,3-diene and 1-aminobenzotriazole yields a mixture of chlorobenzene and o-dichlorobenzene. Oxidation of 1-aminobenzotriazole in the presence of tetraphenylcyclopentadienone leads to 1,2,3,4-tetraphenylnaphthalene via benzyne intermediate [68JCS(CC)1305 69JCS(C)1474] (Scheme 101). 

The meso-ionic 1,3-dithiolium 4-olate (283 R = SMe) exists in equilibrium with the dimer (284 R = SMe). Complete regiospecificity is observed in the 1,3-dipolar cycloaddition of styrene to the diphenyl-derivative (283 R = Ph), which gives only compound (285 R = H,R = Ph) in contrast, methyl acrylate yields a mixture of (285 R = C02Me, R = H) and the isomeric adduct (285 R = H, R = C02Me)/ Irradiation of the diphenyl-compound (283 R = Ph) yields a mixture of 4,5-diphenyl-l,2-dithiole-3-thione (286) via the bridged intermediate shown), sulphur, diphenylacetylene, tetraphenylthiophen, and the latter s precursor, the dithiin (287). The dithiin is thought to arise from the dimeric compound (284 R = Ph) by loss of carbon oxysulphide. ... 

Equimolar amounts of ethyl -p-toluidinocrotonate and benzoin refluxed 24 hrs. with ZnGlg in ethanol ethyl 2-methyl-4,5-diphenyl-l-p-tolylpyrrole-3-carboxy-late. Y 68%. F. e. s. D. M. McKinnon, Can. J. Chem. 43, 2628 (1965) cf. F. Feist, B. 35, 1558 (1902). 

Bromo-l,3-bis-(4-methyl-phenyl sulfonyl)-4,5-diphenyl-l,3,2-diazaborolidine and (45,5. -2-Bromo-13-bis-(4-methylphenyl suIfonyl)-4 -diphenyl-l,3 -diazaborolidine... 

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