1,2-Dioxolane synthesis

Cyclopentane bromohydroperoxides, stereoisomerism, 313, 314 Cyclopentene, primary ozonide, 720 Cycloperoxy chlorination, 1,2-dioxolane synthesis, 238, 240... 

Dioxolane synthesis, 192-273 fused bicyclic dioxolanes, 193, 194 Dioxygenation, stereoselective, 339-48 Dioxymethane, molecular orbital treatment, 28-9... 

The synthesis of 1,3-dioxolanes in combined reaction-rectification process 98MI42. 

A slightly more complex anti arrhythmic agent is pi rmentol (74). It is synthesized from 4-chloropropiophenone (72) by keto group protection as the dioxolane (with ethylene glycol and acid) followed by sodium iodide-mediated alkylation with cis 2,6-dimethyl pi peri dine to give 7. Deblocking with acid followed by addition of 2-1ithiopyridine completes the synthesis of pi rmentol (74). 

In our previous work [8], we rqjorted the synthesis of (2-oxo-l,3-dioxolan-4-yl)methacrylate (DOMA) finrn carbon dioxide and glycidyl methacrylate (GMA) using quaternary salt catalysts. In the present work, we studied the catalytic pra rmance of alkyhnethyl imidazolium salt ionic liquid in the synthesis of polycarbonate from the copolyraerization of CO2 with GMA. The influences of copolymerization variable like catalyst structure and reaction tenperature on the conversion of GMA and the yield of the polycarbonate have been discussed. 

Scheme 21.5 Synthesis of diethyl 2-substituted-[l,3]-dioxolane-4,5-diaeetate.

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